Entity Details

Primary name TTL12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14166
EntryNameTTL12_HUMAN
FullNameTubulin--tyrosine ligase-like protein 12
TaxID9606
Evidenceevidence at protein level
Length644
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesTTLL12

GO terms

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GOName
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005815 microtubule organizing center
GO:0005819 spindle
GO:0007346 regulation of mitotic cell cycle
GO:0015631 tubulin binding
GO:0018215 protein phosphopantetheinylation
GO:0030496 midbody
GO:0034968 histone lysine methylation
GO:0045087 innate immune response
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:1990889 H4K20me3 modified histone binding

Subcellular Location

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Subcellular Location
Cytoplasm
Midbody
Nucleus

Domains

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DomainNameCategoryType
IPR004344 Tubulin-tyrosine ligase/Tubulin polyglutamylaseFamilyFamily
IPR013815 ATP-grasp fold, subdomain 1FamilyHomologous superfamily
IPR027749 Tubulin--tyrosine ligase-like protein 12FamilyFamily

Diseases

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