Entity Details

Primary name GLI2
Entity type gene
Source Source Link

Details

PrimaryID2736
RefseqGeneNG_009030
SymbolGLI2
NameGLI family zinc finger 2
Chromosome2
Location2q14.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1990-01-05
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsGLI2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001501 skeletal system development
GO:0001649 osteoblast differentiation
GO:0001701 in utero embryonic development
GO:0001822 kidney development
GO:0002062 chondrocyte differentiation
GO:0002076 osteoblast development
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0005929 cilium
GO:0005930 axoneme
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007224 smoothened signaling pathway
GO:0007389 pattern specification process
GO:0007411 axon guidance
GO:0007418 ventral midline development
GO:0007442 hindgut morphogenesis
GO:0007507 heart development
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0009913 epidermal cell differentiation
GO:0009952 anterior/posterior pattern specification
GO:0009954 proximal/distal pattern formation
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0021508 floor plate formation
GO:0021513 spinal cord dorsal/ventral patterning
GO:0021517 ventral spinal cord development
GO:0021696 cerebellar cortex morphogenesis
GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
GO:0021965 spinal cord ventral commissure morphogenesis
GO:0021983 pituitary gland development
GO:0030324 lung development
GO:0030879 mammary gland development
GO:0030902 hindbrain development
GO:0031069 hair follicle morphogenesis
GO:0031514 motile cilium
GO:0032331 negative regulation of chondrocyte differentiation
GO:0033089 positive regulation of T cell differentiation in thymus
GO:0035295 tube development
GO:0042475 odontogenesis of dentin-containing tooth
GO:0042733 embryonic digit morphogenesis
GO:0043066 negative regulation of apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0045666 positive regulation of neuron differentiation
GO:0045740 positive regulation of DNA replication
GO:0045879 negative regulation of smoothened signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048566 embryonic digestive tract development
GO:0048589 developmental growth
GO:0048666 neuron development
GO:0048754 branching morphogenesis of an epithelial tube
GO:0060032 notochord regression
GO:0060513 prostatic bud formation
GO:0060603 mammary gland duct morphogenesis
GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:0071407 cellular response to organic cyclic compound
GO:0090103 cochlea morphogenesis
GO:0097542 ciliary tip
GO:0097546 ciliary base
GO:0098586 cellular response to virus
GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
GLI2BTRCBioGRID, IntAct25670079 29429990 details
GLI2CREB1BioGRID, HPRD10074179 details
GLI2SUFUBioGRID, HPRD10564661 details
GLI2ZIC1BioGRID, HPRD11238441 details
GLI2SKIBioGRID, HPRD12435627 details
GLI2SPOPBioGRID25204354 28032859 28805822 details
GLI2TAF9BioGRID26282181 details
GLI2ARBioGRID29429990 details
GLI2OTUB2BioGRID30241937 details
GLI2SMAD3IntAct25670079 details
GLI2ZIC2BioGRID, HPRD11238441 details
GLI2STK36BioGRID, HPRD10806483 details
GLI2HDAC1BioGRID20081843 details
GLI2USP7BioGRID26120032 details
GLI2CUL3BioGRID27477274 details
GLI2USP21BioGRID27621083 details
GLI2ZNF521BioGRID31558698 details
GLI2FBXW11HPRD16651270 details
GLI2EGLN3BioGRID, IntAct26972000 details
GLI2SMAD2IntAct25670079 details
GLI2YWHAZIntAct25670079 details
GLI2SMAD4IntAct25670079 details
GLI2RNF4BioGRID29180619 details
GLI2CHD7IntAct21532573 details
GLI2SOX2IntAct21532573 details
GLI2H1-4IntAct25490446 details
GLI2BCORIntAct25490446 details
GLI2SIRT1IntAct25490446 details
GLI2H4-16IntAct25490446 details
GLI2H4C15IntAct25490446 details
GLI2H4C9IntAct25490446 details
GLI2H4C1IntAct25490446 details
GLI2H4C4IntAct25490446 details
GLI2H4C6IntAct25490446 details
GLI2H4C12IntAct25490446 details
GLI2H4C11IntAct25490446 details
GLI2H4C3IntAct25490446 details
GLI2H4C8IntAct25490446 details
GLI2H4C2IntAct25490446 details
GLI2H4C5IntAct25490446 details
GLI2H4C13IntAct25490446 details
GLI2H4C14IntAct25490446 details
GLI2HNRNPLBioGRID28611215 details
GLI2VIRMABioGRID29507755 details
GLI2MKRN2BioGRID32460013 details