Entity Details

Primary name PO6F1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14863
EntryNamePO6F1_HUMAN
FullNamePOU domain, class 6, transcription factor 1
TaxID9606
Evidenceevidence at protein level
Length301
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPOU6F1

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007420 brain development
GO:0007507 heart development
GO:0007517 muscle organ development
GO:0043565 sequence-specific DNA binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

Show/Hide Table
Subcellular Location
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000327 POU-specific domainDomainDomain
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR010982 Lambda repressor-like, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR013847 POU domainDomainDomain

Diseases

Show/Hide Table

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
PO6F1_HUMANBACH_HUMANBioGRID, IntAct32296183 details
PO6F1_HUMANNFYC_HUMANBioGRID, IntAct32296183 details
PO6F1_HUMANERBB2_HUMANBioGRID, IntAct31980649 details