Entity Details

Primary name IDH2
Entity type gene
Source Source Link

Details

PrimaryID3418
RefseqGeneNG_023302
SymbolIDH2
Nameisocitrate dehydrogenase (NADP(+)) 2
Chromosome15
Location15q26.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-11-02
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsIDHP_HUMAN

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0004450 isocitrate dehydrogenase (NADP+) activity
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005777 peroxisome
GO:0005829 cytosol
GO:0005975 carbohydrate metabolic process
GO:0006097 glyoxylate cycle
GO:0006099 tricarboxylic acid cycle
GO:0006102 isocitrate metabolic process
GO:0006103 2-oxoglutarate metabolic process
GO:0006739 NADP metabolic process
GO:0006741 NADP biosynthetic process
GO:0051287 NAD binding
GO:0060253 negative regulation of glial cell proliferation
GO:0070062 extracellular exosome
GO:1903976 negative regulation of glial cell migration
GO:1904465 negative regulation of matrix metallopeptidase secretion

Diseases

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Interactions

131 interactions

InteractorPartnerSourcesPublicationsLink
IDH2PYGLBioGRID, IntAct21988832 details
IDH2IDH2DIP23558173 details
IDH2FBXO7BioGRID27503909 details
IDH2EIF5BBioGRID, IntAct27173435 unassigned1312 details
IDH2ANXA5BioGRID, IntAct27173435 unassigned1312 details
IDH2GPIBioGRID, IntAct27173435 unassigned1312 details
IDH2PDIA3BioGRID, IntAct27173435 unassigned1312 details
IDH2PA2G4BioGRID, IntAct27173435 unassigned1312 details
IDH2MRPL12BioGRID, IntAct27173435 unassigned1312 details
IDH2SNRPB2BioGRID, IntAct27173435 unassigned1312 details
IDH2ZNF207BioGRID, IntAct27173435 unassigned1312 details
IDH2UBE2NBioGRID, IntAct27173435 unassigned1312 details
IDH2TRAP1BioGRID, IntAct27173435 unassigned1312 details
IDH2SND1BioGRID, IntAct27173435 unassigned1312 details
IDH2CRNNBioGRID, IntAct27173435 unassigned1312 details
IDH2SLC2A4HPRD16396496 details
IDH2HDAC1BioGRID, IntAct23752268 details
IDH2JUNMINT25609649 details
IDH2SIRT4IntAct25525879 details
IDH2KBTBD7BioGRID, IntAct26496610 details
IDH2FASTKD3IntAct20869947 details
IDH2BCAR1bhf-ucl28007913 details
IDH2HSCBBioGRID, IntAct28380382 details
IDH2MAS1BioGRID, IntAct28514442 details
IDH2SLC15A1BioGRID, IntAct28514442 details
IDH2GLMPBioGRID, IntAct28514442 details
IDH2SLC39A9BioGRID, IntAct28514442 details
IDH2KCMF1BioGRID, IntAct26186194 28514442 details
IDH2SOAT1BioGRID, IntAct29128334 details
IDH2LRRK2IntAct31046837 details
IDH2CEBPDBioGRID, IntAct30833792 details
IDH2IRF2BioGRID, IntAct30833792 details
IDH2NAPABioGRID, IntAct30833792 details
IDH2KDM4CBioGRID, MINT24981860 details
IDH2KDM4DBioGRID, MINT24981860 details
IDH2TAGLNMINT32774160 details
IDH2CDK2BioGRID21319273 details
IDH2ADRB2BioGRID23798571 details
IDH2EGFRBioGRID24797263 details
IDH2IDH1BioGRID26344197 details
IDH2G6PDBioGRID26344197 details
IDH2IDH3ABioGRID26344197 details
IDH2IDH3BBioGRID26344197 details
IDH2IDH3GBioGRID26344197 details
IDH2NTRK1BioGRID25921289 details
IDH2ZNF746BioGRID25315684 details
IDH2CFTRBioGRID26618866 details
IDH2SNAI1BioGRID29331416 details
IDH2AGR2BioGRID30575818 details
IDH2TGFBR2BioGRID28443643 details
IDH2USP14BioGRID30425250 details
IDH2NR2C2BioGRID30463901 details
IDH2UBQLN2BioGRID30442662 details
IDH2GATD3BioGRID31536960 32877691 details
IDH2TPP1BioGRID31536960 details
IDH2TSTBioGRID31536960 details
IDH2PKMBioGRID31536960 details
IDH2FABP3BioGRID31536960 details
IDH2LYPLAL1BioGRID31536960 details
IDH2DSTNBioGRID31536960 details
IDH2GLRX5BioGRID31536960 details
IDH2CTSBBioGRID31536960 details
IDH2ACAA2BioGRID31536960 details
IDH2ALDH4A1BioGRID31536960 details
IDH2PMPCABioGRID31536960 details
IDH2ICAM1BioGRID31536960 details
IDH2PTRHD1BioGRID31536960 details
IDH2LAP3BioGRID31536960 details
IDH2ISOC2BioGRID31536960 details
IDH2INHBABioGRID31536960 details
IDH2AIFM1BioGRID31536960 details
IDH2SOD2BioGRID31536960 details
IDH2ACAT1BioGRID31536960 details
IDH2CLIC4BioGRID31536960 details
IDH2RAB11ABioGRID31536960 details
IDH2SCP2BioGRID31536960 details
IDH2FXNBioGRID31536960 details
IDH2HADHBioGRID31536960 details
IDH2LGALS3BioGRID31536960 details
IDH2FAHD1BioGRID31536960 details
IDH2ARCN1BioGRID31536960 details
IDH2CLIC1BioGRID31536960 details
IDH2ENO1BioGRID31536960 details
IDH2FDX1BioGRID31536960 details
IDH2GCSHBioGRID31536960 details
IDH2GSTP1BioGRID31536960 details
IDH2COA7BioGRID31536960 details
IDH2FDX2BioGRID31536960 details
IDH2GRHPRBioGRID31536960 details
IDH2HINT2BioGRID31536960 details
IDH2NENFBioGRID31536960 details
IDH2PARK7BioGRID31536960 details
IDH2PDP1BioGRID31536960 details
IDH2TPI1BioGRID31536960 details
IDH2NDUFAB1BioGRID31536960 details
IDH2PGM1BioGRID31536960 details
IDH2PRDX6BioGRID31536960 details
IDH2TXNL1BioGRID31536960 details
IDH2UCHL1BioGRID31536960 details
IDH2ITFG1BioGRID25437307 details
IDH2BIRC3BioGRID30948266 details
IDH2TRIM28BioGRID29955894 details
IDH2PLEKHA4BioGRID31091453 details
IDH2KIF14BioGRID31586073 details
IDH2KIF23BioGRID31586073 details
IDH2INSBioGRID32457219 details
IDH2ERP44BioGRID24981860 details
IDH2SMCHD1BioGRID24981860 details
IDH2SF3A3BioGRID24981860 details
IDH2SHMT2BioGRID24981860 details
IDH2EPB41L3BioGRID24981860 details
IDH2ACO2BioGRID24981860 details
IDH2RIF1BioGRID24981860 details
IDH2SF3A1BioGRID24981860 details
IDH2CANXBioGRID24981860 details
IDH2ACTN4BioGRID24981860 details
IDH2TRIM21BioGRID24981860 details
IDH2ALDH18A1BioGRID24981860 details
IDH2CNBPBioGRID24981860 details
IDH2RNF5BioGRID32614325 details
IDH2RNF103BioGRID32614325 details
IDH2RNF170BioGRID32614325 details
IDH2RNF185BioGRID32614325 details
IDH2RNFT1BioGRID32614325 details
IDH2TRIM13BioGRID32614325 details
IDH2ZNRF4BioGRID32614325 details
IDH2UFL1BioGRID32807901 details
IDH2DDRGK1BioGRID32807901 details
IDH2AARS2BioGRID34079125 details
IDH2CSBioGRID34079125 details
IDH2PDHA1BioGRID34079125 details