Entity Details

Primary name IL2RB
Entity type gene
Source Source Link

Details

PrimaryID3560
RefseqGene
SymbolIL2RB
Nameinterleukin 2 receptor subunit beta
Chromosome22
Location22q12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1990-06-12
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsIL2RB_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0004911 interleukin-2 receptor activity
GO:0005768 endosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005893 interleukin-2 receptor complex
GO:0007165 signal transduction
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016032 viral process
GO:0019221 cytokine-mediated signaling pathway
GO:0019976 interleukin-2 binding
GO:0035723 interleukin-15-mediated signaling pathway
GO:0038110 interleukin-2-mediated signaling pathway
GO:0042010 interleukin-15 receptor activity
GO:0043066 negative regulation of apoptotic process
GO:0050766 positive regulation of phagocytosis
GO:0065003 protein-containing complex assembly

Diseases

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Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
IL2RBSTAT5ABioGRID, HPRD, MINT10602027 20816854 details
IL2RBSTAT5BBioGRID, HPRD, MINT10602027 details
IL2RBSHBBioGRID, HPRD, MINT12200137 details
IL2RBIL15HPRD, InnateDB, IntAct23104097 25416956 8026467 9176231 details
IL2RBTRIP13BioGRID, IntAct32296183 details
IL2RBIL2DIP, HPRD11035066 16477002 22446627 8049354 details
IL2RBRACK1BioGRID, HPRD12960323 details
IL2RBSHC1BioGRID, HPRD10602027 8294403 details
IL2RBGRB2BioGRID, HPRD10602027 details
IL2RBSTAT1BioGRID, HPRD10602027 details
IL2RBSTAT3BioGRID, HPRD10602027 details
IL2RBJAK1BioGRID, HPRD12133952 20816854 7973658 7973659 8041779 8700888 9553136 9774657 details
IL2RBSOCS1BioGRID, HPRD11133764 29674694 29991678 details
IL2RBHGSBioGRID18445679 21362618 details
IL2RBSOCS3BioGRID, HPRD10373548 details
IL2RBIL2RGBioGRID, HPRD11886175 20816854 details
IL2RBIL15RAHPRD, InnateDB23104097 7641685 details
IL2RBCISHBioGRID, HPRD10514520 details
IL2RBJAK2BioGRID9553136 details
IL2RBNEDD4BioGRID19615332 details
IL2RBLCKBioGRID, HPRD10214954 2047859 21834013 details
IL2RBECM1BioGRID21217760 details
IL2RBACTA1BioGRID20816854 details
IL2RBTUBA1ABioGRID20816854 details
IL2RBJAK3BioGRID, HPRD10825200 20816854 7973659 9553136 details
IL2RBPIK3R1BioGRID, HPRD7509794 9774657 details
IL2RBFYNHPRD8483935 details
IL2RBRAF1HPRD1639773 details
IL2RBLYNHPRD1557373 details
IL2RBPTPN6HPRD9520455 details
IL2RBSYKHPRD7600304 details
IL2RBIL2RAHPRD11886175 details
IL2RBEIF3BHPRD7693677 details
IL2RBMCM2BioGRID25963833 details
IL2RBMTDHBioGRID22199357 details