Entity Details

Primary name LAG3
Entity type gene
Source Source Link

Details

PrimaryID3902
RefseqGene
SymbolLAG3
Namelymphocyte activating 3
Chromosome12
Location12p13.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-02-24
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsLAG3_HUMAN

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002270 plasmacytoid dendritic cell activation
GO:0003823 antigen binding
GO:0004888 transmembrane signaling receptor activity
GO:0005576 extracellular region
GO:0005886 plasma membrane
GO:0007166 cell surface receptor signaling pathway
GO:0009897 external side of plasma membrane
GO:0016021 integral component of membrane
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0032703 negative regulation of interleukin-2 production
GO:0042289 MHC class II protein binding
GO:0045590 negative regulation of regulatory T cell differentiation
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0050776 regulation of immune response

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
LAG3CEBPZHPRD11592063 details
LAG3CENPJHPRD11592063 details