Entity Details

Primary name MBP
Entity type gene
Source Source Link

Details

PrimaryID4155
RefseqGene
SymbolMBP
Namemyelin basic protein
Chromosome18
Location18q23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1992-12-07
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMBP_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0002020 protease binding
GO:0005516 calmodulin binding
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006955 immune response
GO:0007268 chemical synaptic transmission
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0007605 sensory perception of sound
GO:0008366 axon ensheathment
GO:0009636 response to toxic substance
GO:0009986 cell surface
GO:0019911 structural constituent of myelin sheath
GO:0021762 substantia nigra development
GO:0032755 positive regulation of interleukin-6 production
GO:0032991 protein-containing complex
GO:0033269 internode region of axon
GO:0034115 negative regulation of heterotypic cell-cell adhesion
GO:0035633 maintenance of blood-brain barrier
GO:0042552 myelination
GO:0043025 neuronal cell body
GO:0043209 myelin sheath
GO:0043218 compact myelin
GO:0045202 synapse
GO:0061024 membrane organization
GO:0071944 cell periphery
GO:1904685 positive regulation of metalloendopeptidase activity
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production

Diseases

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Interactions

102 interactions

InteractorPartnerSourcesPublicationsLink
MBPPBKMINT10779557 details
MBPAPTXBioGRID, HPRD, IntAct16713569 details
MBPATN1BioGRID, HPRD, IntAct16713569 details
MBPATXN1BioGRID, HPRD, IntAct16713569 details
MBPAPPIntAct16049941 32814053 details
MBPMAPK1BioGRID, HPRD, MINT10371216 10464310 10958680 10978313 11258664 11570821 11983899 12114318 12588875 12760422 12944901 14530346 15380617 17255944 17906618 22778266 8846788 9596579 9792705 details
MBPPDGFRLBioGRID, MINT24412244 details
MBPCTDSP1BioGRID, HPRD, IntAct14743429 25416956 28514442 31515488 32296183 details
MBPPLEKHF2BioGRID, IntAct32296183 details
MBPCTDSPLBioGRID, IntAct28514442 32296183 details
MBPCALM1DIP22405011 details
MBPCALM2DIP22405011 details
MBPCALM3DIP22405011 details
MBPADRB2BioGRID, MINT28298427 details
MBPCCR1BioGRID, MINT28298427 details
MBPPTAFRBioGRID, MINT28298427 details
MBPTRPM7BioGRID, HPRD14594813 details
MBPPRMT5BioGRID, HPRD11152681 details
MBPSTK39BioGRID, HPRD10980603 details
MBPPLP1BioGRID, HPRD2467009 6083474 details
MBPTSSK6BioGRID15870294 details
MBPIRAK4BioGRID15927069 details
MBPPRKCABioGRID, HPRD15927069 2413024 details
MBPPRKCIBioGRID, HPRD10383403 21315177 details
MBPPRKCZBioGRID, HPRD10383403 17639074 21315177 details
MBPPPP2R5CBioGRID15380617 details
MBPLIMK1BioGRID8537403 details
MBPLIMK2BioGRID8537403 details
MBPTBK1BioGRID17599067 details
MBPIKBKEBioGRID17599067 details
MBPSTK3BioGRID20212043 details
MBPMAPK14BioGRID, HPRD10708586 10978313 12429732 15728454 17906618 details
MBPLRRK2BioGRID16269541 17260967 17584768 17706965 19826009 21806997 details
MBPPRKDCBioGRID15147269 details
MBPMAPK12BioGRID17906618 details
MBPMAPK11BioGRID, HPRD15728454 17906618 details
MBPMAPK13BioGRID, HPRD17906618 9207191 details
MBPMAPK3BioGRID, HPRD10339476 11570821 14530346 17906618 19910486 details
MBPCDK1BioGRID17906618 details
MBPCDK5BioGRID17906618 details
MBPMAP3K5BioGRID19293155 details
MBPTLK1BioGRID, HPRD10523312 12955071 details
MBPMELKBioGRID, HPRD16216881 details
MBPCDK7BioGRID15328539 details
MBPCDK8BioGRID15328539 details
MBPCDK9BioGRID15328539 8170997 details
MBPHIPK2BioGRID11120354 details
MBPSQSTM1BioGRID14702098 details
MBPPKN1BioGRID15791647 details
MBPULK1BioGRID18936157 23524951 details
MBPPRKCBBioGRID24681954 details
MBPMAP3K3BioGRID24975362 details
MBPABL1BioGRID19470755 details
MBPRPS6KA5BioGRID, HPRD9873047 details
MBPMAP3K1BioGRID12624112 details
MBPMAPK8BioGRID10978313 details
MBPPTPRABioGRID23532252 details
MBPPRKCDBioGRID, HPRD11964256 12097319 details
MBPILKBioGRID11402068 details
MBPAURKABioGRID20596670 details
MBPRAF1BioGRID15886202 details
MBPMAP2K1BioGRID8617731 details
MBPRXRBIntAct20195357 details
MBPHLA-DRABioGRID, HPRD, InnateDB21131964 9782128 details
MBPTSC1MINT21653829 details
MBPDDX58BioGRID23264040 details
MBPKCNH5BioGRID18458804 details
MBPEEA1BioGRID31184779 details
MBPLAMP1BioGRID31184779 details
MBPCTSDBioGRID31184779 details
MBPPAK1HPRD14579272 details
MBPIRAK1HPRD10346818 details
MBPTRAF6HPRD10346818 details
MBPMAGHPRD12237860 details
MBPMMP7HPRD8786845 details
MBPRANHPRD12101123 details
MBPPRKACAHPRD2413024 details
MBPPRMT1HPRD4924231 details
MBPDYRK1BHPRD10910078 details
MBPSTK4HPRD7665586 details
MBPSTK26HPRD11641781 details
MBPRTN4HPRD12377379 details
MBPCLK1HPRD8798720 details
MBPMAPKAPK5HPRD9628874 details
MBPMKNK1HPRD9155018 details
MBPBMP2KHPRD11500515 details
MBPTLK2HPRD10523312 details
MBPCDK12HPRD11683387 details
MBPNEK9HPRD11864968 details
MBPSRPK1HPRD10390541 details
MBPMICU2HPRD11124993 details
MBPMAPK15HPRD11875070 details
MBPIDEBioGRID, IntAct28514442 details
MBPNLNBioGRID, IntAct28514442 details
MBPPRNPUniProt28671123 details
MBPNCK1BioGRID, IntAct31980649 details
MBPRPS6KA6BioGRID22939629 details
MBPMYH6BioGRID26496610 details
MBPHRASBioGRID30639242 details
MBPHNRNPLBioGRID28611215 details
MBPDDX54BioGRID23239230 details
MBPVIRMABioGRID29507755 details