Entity Details

Primary name NKX6-1
Entity type gene
Source Source Link

Details

PrimaryID4825
RefseqGene
SymbolNKX6-1
NameNK6 homeobox 1
Chromosome4
Location4q21.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-21
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNKX61_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001764 neuron migration
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0007224 smoothened signaling pathway
GO:0009887 animal organ morphogenesis
GO:0021953 central nervous system neuron differentiation
GO:0030154 cell differentiation
GO:0030516 regulation of axon extension
GO:0031016 pancreas development
GO:0032024 positive regulation of insulin secretion
GO:0035094 response to nicotine
GO:0042493 response to drug
GO:0044342 type B pancreatic cell proliferation
GO:0045666 positive regulation of neuron differentiation
GO:0045686 negative regulation of glial cell differentiation
GO:0045687 positive regulation of glial cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048709 oligodendrocyte differentiation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051594 detection of glucose
GO:0070062 extracellular exosome
GO:0071345 cellular response to cytokine stimulus
GO:0071375 cellular response to peptide hormone stimulus
GO:0072560 type B pancreatic cell maturation
GO:2000078 positive regulation of type B pancreatic cell development
GO:2001222 regulation of neuron migration

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
NKX6-1RBPJBioGRID, MINT25609649 details
NKX6-1FBXL13BioGRID29348145 details
NKX6-1INSBioGRID32457219 details