Entity Details

Primary name OAS3
Entity type gene
Source Source Link

Details

PrimaryID4940
RefseqGene
SymbolOAS3
Name2'-5'-oligoadenylate synthetase 3
Chromosome12
Location12q24.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-08
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsOAS3_HUMAN

GO terms

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GOName
GO:0001730 2'-5'-oligoadenylate synthetase activity
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006139 nucleobase-containing compound metabolic process
GO:0009615 response to virus
GO:0016020 membrane
GO:0032728 positive regulation of interferon-beta production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035395 negative regulation of chemokine (C-X-C motif) ligand 9 production
GO:0039529 RIG-I signaling pathway
GO:0039530 MDA-5 signaling pathway
GO:0042742 defense response to bacterium
GO:0043231 intracellular membrane-bounded organelle
GO:0045071 negative regulation of viral genome replication
GO:0046872 metal ion binding
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0060339 negative regulation of type I interferon-mediated signaling pathway
GO:0060700 regulation of ribonuclease activity
GO:0071639 positive regulation of monocyte chemotactic protein-1 production
GO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production
GO:0071659 negative regulation of IP-10 production
GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production

Diseases

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Interactions

49 interactions

InteractorPartnerSourcesPublicationsLink
OAS3MAVSBioGRID, IntAct21903422 details
OAS3IFRD2BioGRID, IntAct21903422 details
OAS3FTSJ3BioGRID, IntAct21903422 details
OAS3DHX30BioGRID, IntAct21903422 details
OAS3EIF6BioGRID, IntAct21903422 details
OAS3PPM1GBioGRID, IntAct21903422 details
OAS3TOP1BioGRID, IntAct21903422 details
OAS3LYARBioGRID, IntAct21903422 details
OAS3PABPC4BioGRID, IntAct21903422 details
OAS3ZNF622BioGRID, IntAct21903422 30833792 details
OAS3H1-2BioGRID, IntAct21903422 details
OAS3GNL3BioGRID, IntAct21903422 details
OAS3GTPBP4BioGRID, IntAct21903422 30833792 details
OAS3CCDC22BioGRID, IntAct26496610 details
OAS3NUDCD1MINT29021621 details
OAS3MKI67BioGRID, IntAct26949251 details
OAS3RFC4BioGRID, IntAct30833792 details
OAS3GPD2BioGRID, IntAct30833792 details
OAS3C11orf98BioGRID, IntAct30833792 details
OAS3TLN1BioGRID, IntAct30833792 details
OAS3NOP16BioGRID, IntAct30833792 details
OAS3G3BP2BioGRID, IntAct30833792 details
OAS3PRPF19BioGRID, IntAct30833792 details
OAS3NOP53BioGRID, IntAct30833792 details
OAS3SDAD1BioGRID, IntAct30833792 details
OAS3GNL3LBioGRID, IntAct30833792 details
OAS3EXOSC3BioGRID, IntAct30833792 details
OAS3NOP10BioGRID, IntAct30833792 details
OAS3LLPHBioGRID, IntAct30833792 details
OAS3CDC5LBioGRID, IntAct30833792 details
OAS3CAPRIN1BioGRID, IntAct30833792 details
OAS3GNL2BioGRID, IntAct30833792 details
OAS3EXOSC10BioGRID, IntAct30833792 details
OAS3RPL39BioGRID, IntAct30833792 details
OAS3MCM2BioGRID, IntAct30833792 details
OAS3MTREXBioGRID, IntAct30833792 details
OAS3H1-5BioGRID, IntAct30833792 details
OAS3RPLP1BioGRID, IntAct30833792 details
OAS3CHMP1ABioGRID22939629 details
OAS3NTRK1BioGRID25921289 details
OAS3ESR2BioGRID29509190 details
OAS3MYCBioGRID29467282 details
OAS3CNPBioGRID30833792 details
OAS3PTBP1BioGRID30833792 details
OAS3CITBioGRID31586073 details
OAS3BRPF3BioGRID31753913 details
OAS3SP110BioGRID31753913 details
OAS3FBP1BioGRID32041737 details
OAS3VIRMABioGRID29507755 details