Entity Details

Primary name PKD1
Entity type gene
Source Source Link

Details

PrimaryID5310
RefseqGeneNG_008617
SymbolPKD1
Namepolycystin 1, transient receptor potential channel interacting
Chromosome16
Location16p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-24
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsPKD1_HUMAN

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001502 cartilage condensation
GO:0001701 in utero embryonic development
GO:0001822 kidney development
GO:0001889 liver development
GO:0001892 embryonic placenta development
GO:0002133 polycystin complex
GO:0005262 calcium channel activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005929 cilium
GO:0006611 protein export from nucleus
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007160 cell-matrix adhesion
GO:0007161 calcium-independent cell-matrix adhesion
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0007507 heart development
GO:0009653 anatomical structure morphogenesis
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016328 lateral plasma membrane
GO:0018105 peptidyl-serine phosphorylation
GO:0019901 protein kinase binding
GO:0019904 protein domain specific binding
GO:0021510 spinal cord development
GO:0021915 neural tube development
GO:0030010 establishment of cell polarity
GO:0030155 regulation of cell adhesion
GO:0030246 carbohydrate binding
GO:0030660 Golgi-associated vesicle membrane
GO:0031514 motile cilium
GO:0032092 positive regulation of protein binding
GO:0034405 response to fluid shear stress
GO:0034703 cation channel complex
GO:0034704 calcium channel complex
GO:0036303 lymph vessel morphogenesis
GO:0042813 Wnt-activated receptor activity
GO:0042994 cytoplasmic sequestering of transcription factor
GO:0043588 skin development
GO:0044325 transmembrane transporter binding
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048565 digestive tract development
GO:0048754 branching morphogenesis of an epithelial tube
GO:0048806 genitalia development
GO:0050982 detection of mechanical stimulus
GO:0051216 cartilage development
GO:0051290 protein heterotetramerization
GO:0060170 ciliary membrane
GO:0060236 regulation of mitotic spindle organization
GO:0060271 cilium assembly
GO:0060428 lung epithelium development
GO:0060674 placenta blood vessel development
GO:0061136 regulation of proteasomal protein catabolic process
GO:0070062 extracellular exosome
GO:0070588 calcium ion transmembrane transport
GO:0072164 mesonephric tubule development
GO:0072177 mesonephric duct development
GO:0072205 metanephric collecting duct development
GO:0072218 metanephric ascending thin limb development
GO:0072237 metanephric proximal tubule development
GO:0072287 metanephric distal tubule morphogenesis
GO:0198738 cell-cell signaling by wnt
GO:2000045 regulation of G1/S transition of mitotic cell cycle

Diseases

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Interactions

46 interactions

InteractorPartnerSourcesPublicationsLink
PKD1ATF7IPHPRD, MINT15231748 details
PKD1ABL1IntAct17474147 details
PKD1FYNIntAct17474147 details
PKD1PKD2bhf-ucl, BioGRID, DIP, HPRD, MINT10097141 11901144 19556541 20168298 21126580 21642537 30093605 9192675 details
PKD1NPHP1BioGRID, MINT20856870 details
PKD1LTB4R2BioGRID, MINT28298427 details
PKD1RGS7BioGRID, HPRD10339594 details
PKD1FN1BioGRID, HPRD11752017 details
PKD1COL1A1BioGRID11752017 details
PKD1KRT18BioGRID, HPRD11581269 details
PKD1COL2A1BioGRID, HPRD11406351 details
PKD1SIAH1BioGRID, HPRD15284290 details
PKD1HDAC9BioGRID15623513 15738054 details
PKD1MARK2BioGRID19011111 details
PKD1PTPRGBioGRID21126580 details
PKD1PIP5K1CBioGRID27775029 details
PKD1NCF1BioGRID20856870 details
PKD1NCK2BioGRID20856870 details
PKD1SRCBioGRID, HPRD11113628 20856870 details
PKD1VIMHPRD11581269 details
PKD1DESHPRD11581269 details
PKD1KRT8HPRD11581269 details
PKD1PKD1BioGRID11901144 details
PKD1ATP1A1BioGRID11901144 details
PKD1JADE1BioGRID23001567 details
PKD1PTK2BioGRID11113628 27775029 details
PKD1CTNNB1BioGRID, HPRD11113628 11274246 details
PKD1GANBioGRID26460568 details
PKD1AKT1BioGRID24462114 details
PKD1PTPRSBioGRID21126580 details
PKD1CDH1BioGRID21126580 details
PKD1JUPHPRD11274246 details
PKD1TLN1HPRD11113628 details
PKD1VCLHPRD11113628 details
PKD1ACTN1HPRD11113628 details
PKD1PXNHPRD11113628 details
PKD1BCAR1HPRD11113628 details
PKD1CTNNA1HPRD11274246 details
PKD1JAK2HPRD12007403 details
PKD1LRRK2IntAct31046837 details
PKD1PRKCZIntAct31980649 details
PKD1CFTRBioGRID17110338 details
PKD1RNF123BioGRID29676528 details
PKD1VIRMABioGRID29507755 details
PKD1APEX1BioGRID28986522 details
PKD1DDX58BioGRID32513696 details