Entity Details

Primary name PPP5C
Entity type gene
Source Source Link

Details

PrimaryID5536
RefseqGeneNG_028163
SymbolPPP5C
Nameprotein phosphatase 5 catalytic subunit
Chromosome19
Location19q13.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-24
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPPP5_HUMAN

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000278 mitotic cell cycle
GO:0001933 negative regulation of protein phosphorylation
GO:0001965 G-protein alpha-subunit binding
GO:0003723 RNA binding
GO:0004721 phosphoprotein phosphatase activity
GO:0004722 protein serine/threonine phosphatase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006302 double-strand break repair
GO:0006351 transcription, DNA-templated
GO:0006470 protein dephosphorylation
GO:0008017 microtubule binding
GO:0008289 lipid binding
GO:0010288 response to lead ion
GO:0016576 histone dephosphorylation
GO:0016791 phosphatase activity
GO:0032991 protein-containing complex
GO:0035970 peptidyl-threonine dephosphorylation
GO:0042802 identical protein binding
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043204 perikaryon
GO:0043231 intracellular membrane-bounded organelle
GO:0043278 response to morphine
GO:0043531 ADP binding
GO:0044877 protein-containing complex binding
GO:0046872 metal ion binding
GO:0048156 tau protein binding
GO:0051879 Hsp90 protein binding
GO:0070262 peptidyl-serine dephosphorylation
GO:0070301 cellular response to hydrogen peroxide
GO:0071276 cellular response to cadmium ion
GO:0101031 chaperone complex
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1901215 negative regulation of neuron death
GO:1904550 response to arachidonic acid
GO:1990635 proximal dendrite
GO:2000324 positive regulation of glucocorticoid receptor signaling pathway

Diseases

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Interactions

144 interactions

InteractorPartnerSourcesPublicationsLink
PPP5CCSE1LBioGRID, HPRD, IntAct16169070 details
PPP5CDISC1BioGRID, IntAct17043677 31413325 details
PPP5CESR2BioGRID, IntAct14764652 details
PPP5CESR1BioGRID, IntAct14764652 details
PPP5CHSP90AA1BioGRID, HPRD, IntAct10400612 15383005 16531226 19740745 19875381 20661446 21235734 21360678 25036637 26496610 27353360 27880917 28330616 9195923 details
PPP5CCDC37BioGRID, IntAct21360678 25036637 28330616 29141220 details
PPP5CHSP90AB1BioGRID, DIP, IntAct16531226 21360678 25036637 26496610 27880917 28330616 details
PPP5CEGFRBioGRID, IntAct20029029 31980649 details
PPP5CMAP3K7BioGRID, MINT21900206 details
PPP5CPPP2R1AHPRD, MINT11504734 details
PPP5CCHORDC1BioGRID, HPRD, IntAct16083881 23414517 25036637 details
PPP5CHTR2ADIP, HPRD16537434 details
PPP5CCRY2BioGRID, DIP, HPRD16790549 9383998 details
PPP5CCDC27BioGRID, HPRD9405394 details
PPP5CGNA12BioGRID, HPRD12176367 details
PPP5CGNA13BioGRID, HPRD12176367 details
PPP5CMAP3K5BioGRID, HPRD11689443 details
PPP5CCDK20BioGRID16954377 details
PPP5CAPPBioGRID21832049 details
PPP5CMAPTBioGRID, HPRD12435421 1330687 15546861 16262633 details
PPP5CHUWE1BioGRID23652204 details
PPP5CCSNK1DBioGRID29141220 details
PPP5CVHLBioGRID29141220 details
PPP5CTP53BP1BioGRID19176521 details
PPP5COGTBioGRID32994395 details
PPP5CCDC16HPRD9405394 details
PPP5CCPNE1HPRD12522145 details
PPP5CCPNE2HPRD12522145 details
PPP5CSTIP1BioGRID, IntAct21360678 28330616 details
PPP5CPPP5CHPRD, IntAct15155720 21360678 details
PPP5CPPP2R3AHPRD, MINT11504734 details
PPP5CPTGES3BioGRID, IntAct20661446 25036637 28330616 details
PPP5CNOL9BioGRID, IntAct28330616 details
PPP5CAGO1BioGRID, IntAct28330616 details
PPP5CAGO3BioGRID, IntAct28330616 details
PPP5CCDK9BioGRID, IntAct28330616 details
PPP5CCLUIntAct31413325 details
PPP5CHSPA4BioGRID15383005 details
PPP5CNR3C1BioGRID20661446 details
PPP5CNR3C2BioGRID20661446 details
PPP5CPGRBioGRID20661446 details
PPP5CARBioGRID20661446 details
PPP5CFLCNBioGRID27353360 details
PPP5CCPNE4HPRD12522145 details
PPP5CUSP49BioGRID, IntAct19615732 details
PPP5CPHLPP1BioGRID, IntAct19615732 details
PPP5CULK2IntAct20562859 details
PPP5CWIPI2IntAct20562859 details
PPP5CGRB2BioGRID, IntAct21706016 details
PPP5CHSPA8BioGRID, IntAct21360678 details
PPP5CCCT4BioGRID, IntAct21360678 details
PPP5CHSPA1AIntAct21360678 details
PPP5CHSPA1BBioGRID, IntAct21360678 details
PPP5CCDK18BioGRID, IntAct23602568 details
PPP5CAHSA1BioGRID, IntAct25036637 details
PPP5CCDC37L1BioGRID, IntAct25036637 details
PPP5CIRS4BioGRID, IntAct25036637 28330616 details
PPP5CABCF2BioGRID, IntAct26496610 details
PPP5CABCF2-H2BE1IntAct26496610 details
PPP5CRPS6KB1BioGRID, IntAct26496610 details
PPP5CUSP45BioGRID, IntAct26496610 details
PPP5CPRPF8BioGRID, IntAct28330616 details
PPP5CRBBP5BioGRID, IntAct28330616 details
PPP5CCDC42BPBBioGRID, IntAct28330616 details
PPP5CELP3BioGRID, IntAct28330616 details
PPP5CRACK1BioGRID, IntAct28330616 details
PPP5CYWHABBioGRID, IntAct28330616 details
PPP5CELP1BioGRID, IntAct28330616 details
PPP5CFLIIBioGRID, IntAct28330616 details
PPP5CSNRNP200BioGRID, IntAct28330616 details
PPP5CDDB1BioGRID, IntAct28330616 details
PPP5CLRRC1BioGRID, IntAct28330616 details
PPP5CBAG2BioGRID, IntAct28330616 details
PPP5CYWHAQBioGRID, IntAct28330616 details
PPP5CHACD3BioGRID, IntAct28330616 details
PPP5CCNTLNBioGRID, IntAct28330616 details
PPP5CSUGT1BioGRID, IntAct28330616 details
PPP5CNUDCBioGRID, IntAct28330616 details
PPP5CCADBioGRID, IntAct28330616 details
PPP5CKSR2IntAct27086506 details
PPP5CPOLD2BioGRID, IntAct28514442 details
PPP5CBPHLBioGRID, IntAct26186194 28514442 details
PPP5CRAB41BioGRID, IntAct28514442 details
PPP5CCRY1DIP16790549 details
PPP5CTPTEP2-CSNK1EDIP16790549 details
PPP5CCSNK1EDIP16790549 details
PPP5CBRD1BioGRID, MINT24981860 details
PPP5CDIS3BioGRID22939629 details
PPP5CAHSGBioGRID22939629 details
PPP5CHNRNPA1BioGRID22939629 details
PPP5CABHD14ABioGRID22863883 details
PPP5CBZW2BioGRID22863883 details
PPP5CEIF6BioGRID22863883 details
PPP5CGINS3BioGRID22863883 details
PPP5CGSSBioGRID22863883 details
PPP5CNAPRTBioGRID22863883 details
PPP5CPAFAH1B2BioGRID22863883 details
PPP5CPAPSS1BioGRID22863883 details
PPP5CPLD3BioGRID22863883 details
PPP5CCTPS1BioGRID22863883 details
PPP5CDCPSBioGRID22863883 details
PPP5CDFFABioGRID22863883 details
PPP5CFUBP1BioGRID22863883 details
PPP5CGAPDHBioGRID22863883 details
PPP5CPPIBBioGRID22863883 details
PPP5CTUFMBioGRID22863883 details
PPP5CVCLBioGRID22863883 details
PPP5CRAP1GDS1BioGRID22863883 details
PPP5CXPO1BioGRID22863883 details
PPP5CDUTBioGRID26344197 details
PPP5CMINPP1BioGRID26344197 details
PPP5CNOL10BioGRID26344197 details
PPP5CPSPC1BioGRID26344197 details
PPP5CTATDN1BioGRID26344197 details
PPP5CNTRK1BioGRID25921289 details
PPP5CPSEN2BioGRID26496610 details
PPP5CRBBP6BioGRID26496610 details
PPP5CHSPA6BioGRID27880917 details
PPP5CDUSP8BioGRID27432908 details
PPP5CTPTEBioGRID27432908 details
PPP5CEGLN3BioGRID26972000 details
PPP5CYAF2BioGRID27684187 details
PPP5CGNAI1BioGRID29141220 details
PPP5CACTG1BioGRID29141220 details
PPP5CVIMBioGRID29141220 details
PPP5CACTBBioGRID29141220 details
PPP5CWWOXBioGRID30619736 details
PPP5CRECQL4BioGRID29229926 details
PPP5CEPM2ABioGRID28675297 details
PPP5CMTMR7BioGRID28675297 details
PPP5CPTENBioGRID28675297 details
PPP5CBIRC3BioGRID30948266 details
PPP5CPLEKHA4BioGRID31091453 details
PPP5CCOPS5BioGRID31950832 details
PPP5CDNAJB13BioGRID33957083 details
PPP5CDNAJC11BioGRID33957083 details
PPP5CDNAJC8BioGRID33957083 details
PPP5CLMAN1BioGRID34079125 details
PPP5CENO1BioGRID22658674 details
PPP5CSHMT2BioGRID22658674 details
PPP5CMOV10BioGRID22658674 details
PPP5CNXF1BioGRID22658674 details
PPP5CTRIM25BioGRID29117863 details
PPP5CTNIP2BioGRID27609421 details