Entity Details

Primary name SPRE3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ2MJR0
EntryNameSPRE3_HUMAN
FullNameSprouty-related, EVH1 domain-containing protein 3
TaxID9606
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesSPRED3

GO terms

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GOName
GO:0000188 obsolete inactivation of MAPK activity
GO:0005886 plasma membrane
GO:0007275 multicellular organism development
GO:0010719 negative regulation of epithelial to mesenchymal transition
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0070373 negative regulation of ERK1 and ERK2 cascade
GO:0090311 regulation of protein deacetylation
GO:1902747 negative regulation of lens fiber cell differentiation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000697 WH1/EVH1 domainDomainDomain
IPR007875 SproutyFamilyFamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR023337 c-Kit-binding domainDomainDomain
IPR041937 SPRE, EVH1 domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SPRE3_HUMANZDH17_HUMANBioGRID24705354 details