Entity Details

Primary name PTPRJ
Entity type gene
Source Source Link

Details

PrimaryID5795
RefseqGeneNG_012209
SymbolPTPRJ
Nameprotein tyrosine phosphatase receptor type J
Chromosome11
Location11p11.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPTPRJ_HUMAN

GO terms

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GOName
GO:0001772 immunological synapse
GO:0004725 protein tyrosine phosphatase activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006470 protein dephosphorylation
GO:0008013 beta-catenin binding
GO:0008285 negative regulation of cell population proliferation
GO:0009986 cell surface
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0016791 phosphatase activity
GO:0019221 cytokine-mediated signaling pathway
GO:0019901 protein kinase binding
GO:0030155 regulation of cell adhesion
GO:0030183 B cell differentiation
GO:0030308 negative regulation of cell growth
GO:0030336 negative regulation of cell migration
GO:0032587 ruffle membrane
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0035579 specific granule membrane
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0043116 negative regulation of vascular permeability
GO:0043312 neutrophil degranulation
GO:0043407 negative regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0045295 gamma-catenin binding
GO:0045296 cadherin binding
GO:0045785 positive regulation of cell adhesion
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050852 T cell receptor signaling pathway
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050918 positive chemotaxis
GO:0051019 mitogen-activated protein kinase binding
GO:0051894 positive regulation of focal adhesion assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0051898 negative regulation of protein kinase B signaling
GO:0060242 contact inhibition
GO:0070062 extracellular exosome
GO:0070097 delta-catenin binding
GO:1905451 positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

Diseases

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Interactions

88 interactions

InteractorPartnerSourcesPublicationsLink
PTPRJPTPRJBioGRID, MINT11526512 15978577 19167335 details
PTPRJCDH2IntAct19167335 details
PTPRJTECIntAct19167335 details
PTPRJERBB2IntAct19167335 details
PTPRJPDGFRBHPRD, IntAct, MINT10821867 12062403 19167335 details
PTPRJMETHPRD, IntAct, MINT12370829 12475979 19167335 details
PTPRJJAK2IntAct19167335 details
PTPRJPXNIntAct19167335 details
PTPRJLCKIntAct19167335 details
PTPRJCTNNB1BioGRID, HPRD, IntAct, MINT12370829 19167335 details
PTPRJINSRIntAct19167335 details
PTPRJTIE1IntAct19167335 details
PTPRJCSKIntAct19167335 details
PTPRJGAB1IntAct, MINT12475979 19167335 details
PTPRJALKIntAct19167335 details
PTPRJGRIN2BIntAct19167335 details
PTPRJPPP1R12AIntAct19167335 details
PTPRJNTRK1IntAct19167335 details
PTPRJPDPK1IntAct19167335 details
PTPRJNSFIntAct19167335 details
PTPRJKITIntAct19167335 details
PTPRJGHRIntAct19167335 details
PTPRJEPORIntAct19167335 details
PTPRJEGFRBioGRID, HPRD, IntAct19167335 19836242 9115287 details
PTPRJMAPK3IntAct, MINT19167335 19494114 details
PTPRJTEKIntAct19167335 details
PTPRJWASIntAct19167335 details
PTPRJTNK2IntAct19167335 details
PTPRJCBLIntAct19167335 details
PTPRJLEPRIntAct19167335 details
PTPRJPKP4IntAct19167335 details
PTPRJLATBioGRID, HPRD, MINT11259588 details
PTPRJKDRMINT18936167 details
PTPRJCTNND1BioGRID, HPRD, MINT12370829 12475979 details
PTPRJFLT1MINT12771128 16893970 details
PTPRJMAPK1MINT19494114 details
PTPRJANP32BBioGRID, MINT24412244 details
PTPRJBAATBioGRID, MINT24412244 details
PTPRJTRMOBioGRID, MINT24412244 details
PTPRJTSTD2BioGRID, MINT24412244 details
PTPRJFANCCBioGRID, MINT24412244 details
PTPRJFBP1BioGRID, MINT24412244 details
PTPRJHEMGNBioGRID, MINT24412244 details
PTPRJHRASBioGRID, MINT24412244 30639242 details
PTPRJMAP2K1BioGRID, MINT24412244 details
PTPRJNANSBioGRID, MINT24412244 details
PTPRJPPP2CBBioGRID, MINT24412244 details
PTPRJPPP3R2BioGRID, MINT24412244 details
PTPRJRASA1BioGRID, MINT24412244 details
PTPRJSFRP4BioGRID, MINT24412244 details
PTPRJMSANTD3-TMEFF1MINT24412244 details
PTPRJTMEFF1BioGRID, MINT24412244 details
PTPRJZNF510BioGRID, MINT24412244 details
PTPRJCASC3BioGRID, MINT25640309 details
PTPRJCYP17A1BioGRID, MINT25640309 details
PTPRJEPSTI1BioGRID, MINT25640309 details
PTPRJHOXC6BioGRID, MINT25640309 details
PTPRJKLK7BioGRID, MINT25640309 details
PTPRJKLK9BioGRID, MINT25640309 details
PTPRJLYPD3BioGRID, MINT25640309 details
PTPRJPRDM14BioGRID, MINT25640309 details
PTPRJBAP1BioGRID, MINT25640309 details
PTPRJTRIM25BioGRID, MINT25640309 29117863 details
PTPRJSDCBPBioGRID, HPRD12403354 details
PTPRJPLCG1BioGRID, HPRD11259588 details
PTPRJJUPHPRD, MINT12370829 details
PTPRJFLT3IntAct23650535 details
PTPRJGRB2BioGRID21706016 details
PTPRJIL2RGHPRD12370829 details
PTPRJNOP2HPRD12370829 9115287 details
PTPRJLGALS8BioGRID, IntAct26186194 28514442 details
PTPRJLGALS9BioGRID, IntAct26186194 28514442 details
PTPRJLGALS3BioGRID, IntAct26186194 28514442 details
PTPRJRPL8BioGRID, IntAct30021884 details
PTPRJFBXO6BioGRID22268729 details
PTPRJCDH1BioGRID25468996 details
PTPRJRINT1BioGRID27880917 details
PTPRJC19orf25BioGRID27880917 details
PTPRJNOS1APBioGRID27880917 details
PTPRJC1orf226BioGRID27880917 details
PTPRJRAB11FIP1BioGRID27880917 details
PTPRJKRASBioGRID30639242 34079125 details
PTPRJRAB11ABioGRID34079125 details
PTPRJSTX7BioGRID34079125 details
PTPRJHNRNPLBioGRID28611215 details
PTPRJVIRMABioGRID29507755 details
PTPRJHNRNPH1BioGRID26760575 details
PTPRJDDX58BioGRID32513696 details