Entity Details

Primary name RFC1
Entity type gene
Source Source Link

Details

PrimaryID5981
RefseqGene
SymbolRFC1
Namereplication factor C subunit 1
Chromosome4
Location4p14
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-18
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsRFC1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0003690 double-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005663 DNA replication factor C complex
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0006261 DNA-dependent DNA replication
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006287 base-excision repair, gap-filling
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006297 nucleotide-excision repair, DNA gap filling
GO:0007004 telomere maintenance via telomerase
GO:0008047 enzyme activator activity
GO:0019904 protein domain specific binding
GO:0019985 translesion synthesis
GO:0031391 Elg1 RFC-like complex
GO:0032201 telomere maintenance via semi-conservative replication
GO:0033683 nucleotide-excision repair, DNA incision
GO:0042276 error-prone translesion synthesis
GO:0042769 DNA damage response, detection of DNA damage
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0061860 DNA clamp unloader activity
GO:0070062 extracellular exosome
GO:0070987 error-free translesion synthesis
GO:0090618 DNA clamp unloading

Diseases

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Interactions

148 interactions

InteractorPartnerSourcesPublicationsLink
RFC1RFC4BioGRID, IntAct18245774 22939629 26344197 28514442 9092549 9488738 details
RFC1RFC3BioGRID, HPRD, IntAct18245774 22939629 26344197 8692848 9488738 details
RFC1CSNK2BBioGRID, MINT21900206 details
RFC1PCNABioGRID, HPRD, IntAct10353443 12045192 12171929 12192049 12400013 15225546 22939629 24958773 26344197 26496610 30301766 8861969 8999859 9092549 9649448 details
RFC1SSBP3BioGRID, IntAct20211142 details
RFC1ZSCAN1BioGRID, IntAct20211142 details
RFC1HDAC1BioGRID, HPRD12045192 details
RFC1BRD4BioGRID, HPRD12192049 31239290 32416067 details
RFC1RELABioGRID, HPRD12509469 details
RFC1MYOCBioGRID, HPRD16289162 details
RFC1YWHAQBioGRID15161933 details
RFC1UBCBioGRID28190767 details
RFC1RFC2BioGRID, HPRD, IntAct, UniProt15655353 18245774 22939629 26344197 9488738 details
RFC1SMC1ABioGRID, HPRD, IntAct16438930 26344197 details
RFC1MYCBioGRID, IntAct17353931 29467282 details
RFC1RFC5BioGRID, IntAct18245774 22939629 26344197 28514442 9488738 details
RFC1ATMBioGRID10783165 details
RFC1BLMBioGRID10783165 details
RFC1BRCA1BioGRID, HPRD10783165 25184681 details
RFC1MLH1BioGRID10783165 details
RFC1MRE11BioGRID10783165 details
RFC1MSH2BioGRID10783165 details
RFC1MSH6BioGRID10783165 details
RFC1NBNBioGRID10783165 details
RFC1RAD50BioGRID10783165 details
RFC1TP53BioGRID12509469 details
RFC1CDK4BioGRID, HPRD10353443 details
RFC1CCND1BioGRID, HPRD10353443 21654808 details
RFC1RB1BioGRID10353443 details
RFC1XRCC5BioGRID12393188 26344197 details
RFC1RAD17BioGRID12400013 18245774 details
RFC1CHTF18BioGRID18245774 details
RFC1PMS1BioGRID17148452 details
RFC1RPA1BioGRID24332808 26474068 details
RFC1SPRTNBioGRID23254330 details
RFC1ATRXBioGRID29937341 details
RFC1TRIM29BioGRID26095369 details
RFC1SOX2BioGRID21280222 details
RFC1RFC1HPRD12192049 details
RFC1CEBPAHPRD12509469 details
RFC1TCEAL1HPRD10353443 details
RFC1CASP3HPRD9235961 9351817 details
RFC1ESR2IntAct21182203 details
RFC1GABARAPL2IntAct20562859 details
RFC1HDGFBioGRID, IntAct21907836 details
RFC1E2F3MINT22157815 details
RFC1YBX1IntAct25497084 details
RFC1JUNMINT25609649 details
RFC1NOP56BioGRID, IntAct26496610 details
RFC1IBTKBioGRID, IntAct26496610 details
RFC1DAXXBioGRID, IntAct26496610 details
RFC1HNRNPUBioGRID, IntAct26496610 details
RFC1LCORIntAct26496610 details
RFC1EMC2BioGRID, IntAct26496610 details
RFC1NOTCH1BioGRID, MINT23022380 details
RFC1FGF3BioGRID, IntAct28514442 details
RFC1RRP8BioGRID, IntAct28514442 details
RFC1THBS3BioGRID, IntAct26186194 28514442 details
RFC1MACROH2A2BioGRID, IntAct28514442 details
RFC1RPL18ABioGRID, IntAct28514442 details
RFC1TEAD2BioGRID, IntAct28514442 details
RFC1AURKAIP1BioGRID, IntAct29568061 details
RFC1FBLBioGRID, IntAct29568061 34079125 details
RFC1H3C1BioGRID, IntAct, MINT25281560 29568061 34079125 details
RFC1H3C4IntAct, MINT25281560 29568061 details
RFC1H3C3IntAct, MINT25281560 29568061 details
RFC1H3C6IntAct, MINT25281560 29568061 details
RFC1H3C11IntAct, MINT25281560 29568061 details
RFC1H3C8IntAct, MINT25281560 29568061 details
RFC1H3C12IntAct, MINT25281560 29568061 details
RFC1H3C10IntAct, MINT25281560 29568061 details
RFC1H3C2IntAct, MINT25281560 29568061 details
RFC1H3C7IntAct, MINT25281560 29568061 details
RFC1RPS6BioGRID, IntAct29568061 34079125 details
RFC1OXR1BioGRID, IntAct30021884 details
RFC1H2BC5MINT25281560 details
RFC1H2BC8BioGRID, MINT25281560 34079125 details
RFC1H2BC7MINT25281560 details
RFC1H2BC6MINT25281560 details
RFC1H2BC10MINT25281560 details
RFC1H2BC4MINT25281560 details
RFC1LRRK2IntAct31046837 details
RFC1VAMP5BioGRID, IntAct30833792 details
RFC1RNF146MINT21799911 details
RFC1RPA3BioGRID, MINT24332808 24981860 details
RFC1SAP25BioGRID16449650 details
RFC1SIRT7BioGRID22586326 details
RFC1LAMP2BioGRID22939629 details
RFC1RBM14BioGRID22939629 details
RFC1WDR18BioGRID22939629 details
RFC1RPA2BioGRID24332808 details
RFC1NIFKBioGRID26186194 details
RFC1NTRK1BioGRID25921289 details
RFC1GLYR1BioGRID26344197 details
RFC1PDS5ABioGRID26344197 details
RFC1RACGAP1BioGRID26344197 details
RFC1CDC45BioGRID26344197 details
RFC1SMC2BioGRID26344197 details
RFC1SMC4BioGRID26344197 details
RFC1XRCC6BioGRID26344197 30585729 details
RFC1NF2BioGRID26549023 details
RFC1HSPA8BioGRID27684187 details
RFC1CSNK1A1BioGRID27684187 details
RFC1PCBP1BioGRID27684187 details
RFC1EFTUD2BioGRID28515276 details
RFC1NKX2-1BioGRID28192407 details
RFC1CHD3BioGRID28977666 details
RFC1CHD4BioGRID28977666 details
RFC1EZH2BioGRID27634302 details
RFC1RECQL4BioGRID29229926 details
RFC1RESTBioGRID27976729 details
RFC1WDR76BioGRID27248496 31353912 details
RFC1H4C1BioGRID27248496 30804502 details
RFC1H2BC3BioGRID27248496 details
RFC1H2AC4BioGRID27248496 details
RFC1GRWD1BioGRID29991511 details
RFC1RC3H1BioGRID30209976 details
RFC1ZBTB7ABioGRID26446488 details
RFC1NR2C2BioGRID30463901 details
RFC1PRDM16BioGRID30462309 details
RFC1MECOMBioGRID30462309 details
RFC1SNRNP70BioGRID29802200 details
RFC1CYLDBioGRID31067453 details
RFC1BIRC3BioGRID30948266 details
RFC1WWP2BioGRID31048545 details
RFC1BRD7BioGRID30940648 details
RFC1TRAIPBioGRID27462463 details
RFC1OBSL1BioGRID31343991 details
RFC1PLEKHA4BioGRID31091453 details
RFC1ANLNBioGRID31586073 details
RFC1MAD2L2BioGRID30154076 details
RFC1KIF23BioGRID31586073 details
RFC1ZNF263BioGRID32051553 details
RFC1MAFBBioGRID31822558 details
RFC1CICBioGRID29844126 details
RFC1IFI16BioGRID31665637 details
RFC1NR3C1BioGRID31182584 details
RFC1DDRGK1BioGRID32160526 32807901 details
RFC1APEX1BioGRID34079125 details
RFC1CBX3BioGRID34079125 details
RFC1POLR1GBioGRID34079125 details
RFC1CENPABioGRID34079125 details
RFC1LMNABioGRID34079125 details
RFC1NUP50BioGRID34079125 details
RFC1RPL31BioGRID34079125 details
RFC1TERF2IPBioGRID34079125 details
RFC1ZNF330BioGRID34079125 details
RFC1VIRMABioGRID29507755 details