Entity Details

Primary name SOX17
Entity type gene
Source Source Link

Details

PrimaryID64321
RefseqGeneNG_028171
SymbolSOX17
NameSRY-box transcription factor 17
Chromosome8
Location8q11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-02-13
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsSOX17_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0001570 vasculogenesis
GO:0001656 metanephros development
GO:0001706 endoderm formation
GO:0001714 endodermal cell fate specification
GO:0001828 inner cell mass cellular morphogenesis
GO:0001947 heart looping
GO:0003142 cardiogenic plate morphogenesis
GO:0003143 embryonic heart tube morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0003308 negative regulation of Wnt signaling pathway involved in heart development
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007283 spermatogenesis
GO:0007493 endodermal cell fate determination
GO:0007507 heart development
GO:0008013 beta-catenin binding
GO:0008134 transcription factor binding
GO:0009653 anatomical structure morphogenesis
GO:0010628 positive regulation of gene expression
GO:0016055 Wnt signaling pathway
GO:0021903 rostrocaudal neural tube patterning
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030154 cell differentiation
GO:0030308 negative regulation of cell growth
GO:0031648 protein destabilization
GO:0035050 embryonic heart tube development
GO:0042074 cell migration involved in gastrulation
GO:0045597 positive regulation of cell differentiation
GO:0045732 positive regulation of protein catabolic process
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045995 regulation of embryonic development
GO:0048617 embryonic foregut morphogenesis
GO:0048866 stem cell fate specification
GO:0050821 protein stabilization
GO:0060214 endocardium formation
GO:0060913 cardiac cell fate determination
GO:0060914 heart formation
GO:0060956 endocardial cell differentiation
GO:0061009 common bile duct development
GO:0061010 gall bladder development
GO:0061031 endodermal digestive tract morphogenesis
GO:0072091 regulation of stem cell proliferation
GO:0072189 ureter development
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1990830 cellular response to leukemia inhibitory factor
GO:2000035 regulation of stem cell division
GO:2000043 regulation of cardiac cell fate specification

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
SOX17APBA3UniProt26948053 details
SOX17CTNNB1bhf-ucl, HPRD15163629 17875931 details
SOX17EEFSECBioGRID, IntAct26496610 details
SOX17RPL38BioGRID, IntAct26496610 details
SOX17HOMER3BioGRID, IntAct26496610 details
SOX17EBNA1BP2BioGRID, IntAct26496610 details
SOX17POU5F1bhf-ucl19736317 details
SOX17EZH2IntAct27728805 details