Entity Details

Primary name SMPD2
Entity type gene
Source Source Link

Details

PrimaryID6610
RefseqGene
SymbolSMPD2
Namesphingomyelin phosphodiesterase 2
Chromosome6
Location6q21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-12-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNSMA_HUMAN

GO terms

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GOName
GO:0004620 phospholipase activity
GO:0004767 sphingomyelin phosphodiesterase activity
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005901 caveola
GO:0006684 sphingomyelin metabolic process
GO:0006685 sphingomyelin catabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0009612 response to mechanical stimulus
GO:0016020 membrane
GO:0030149 sphingolipid catabolic process
GO:0035556 intracellular signal transduction
GO:0046513 ceramide biosynthetic process
GO:0046872 metal ion binding
GO:0071944 cell periphery
GO:2000304 positive regulation of ceramide biosynthetic process

Diseases

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Interactions

42 interactions

InteractorPartnerSourcesPublicationsLink
SMPD2ARFIP1BioGRID, IntAct32296183 details
SMPD2STARBioGRID, IntAct32296183 details
SMPD2SLC10A1BioGRID, IntAct32296183 details
SMPD2PGRMC2BioGRID, IntAct32296183 details
SMPD2PITPNC1BioGRID, IntAct32296183 details
SMPD2GAD2BioGRID, IntAct32296183 details
SMPD2NDRG4BioGRID, IntAct32296183 details
SMPD2COQ8ABioGRID, IntAct32296183 details
SMPD2CCN1BioGRID, IntAct32296183 details
SMPD2TMEM14BBioGRID, IntAct32296183 details
SMPD2SLC7A8BioGRID, IntAct32296183 details
SMPD2TMEM167BBioGRID, IntAct32296183 details
SMPD2SH3GLB1IntAct32814053 details
SMPD2PBX3BioGRID32296183 details
SMPD2TMEM31BioGRID32296183 details
SMPD2PIK3CGHPRD11238738 details
SMPD2CHURC1-FNTBIntAct28514442 details
SMPD2FNTBBioGRID, IntAct26186194 28514442 details
SMPD2LRRTM1BioGRID, IntAct28514442 details
SMPD2PCDHAC2BioGRID, IntAct28514442 details
SMPD2KCNC4BioGRID, IntAct28514442 details
SMPD2TEX28BioGRID, IntAct28514442 details
SMPD2FAM189BBioGRID, IntAct28514442 details
SMPD2PCDHGB4BioGRID, IntAct28514442 details
SMPD2TMED6BioGRID, IntAct28514442 details
SMPD2ZNRF4BioGRID, IntAct28514442 details
SMPD2PCDHB16BioGRID, IntAct28514442 details
SMPD2TMEM30ABioGRID, IntAct26186194 28514442 details
SMPD2PCDHB7BioGRID, IntAct28514442 details
SMPD2PCDHA3BioGRID, IntAct28514442 details
SMPD2PCDHGA5BioGRID, IntAct28514442 details
SMPD2PLVAPBioGRID, IntAct26186194 28514442 details
SMPD2LRRC32BioGRID, IntAct28514442 details
SMPD2RPN2BioGRID, IntAct28514442 34079125 details
SMPD2ANAPC10BioGRID, IntAct26186194 28514442 details
SMPD2MTHFRBioGRID, IntAct26186194 28514442 details
SMPD2CDY2BMINT24981860 details
SMPD2CDY2ABioGRID, MINT24981860 details
SMPD2HLA-DQA1BioGRID26186194 details
SMPD2SRPRBBioGRID26186194 details
SMPD2OTULINLBioGRID31056421 details
SMPD2HSD17B11BioGRID34079125 details