Entity Details

Primary name BPI
Entity type gene
Source Source Link

Details

PrimaryID671
RefseqGeneNG_047016
SymbolBPI
Namebactericidal permeability increasing protein
Chromosome20
Location20q11.23
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-04-26
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBPI_HUMAN

GO terms

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GOName
GO:0001530 lipopolysaccharide binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0010494 cytoplasmic stress granule
GO:0016020 membrane
GO:0019730 antimicrobial humoral response
GO:0019731 antibacterial humoral response
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0032715 negative regulation of interleukin-6 production
GO:0032717 negative regulation of interleukin-8 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0035578 azurophil granule lumen
GO:0035580 specific granule lumen
GO:0043031 negative regulation of macrophage activation
GO:0043312 neutrophil degranulation
GO:0045087 innate immune response
GO:0050829 defense response to Gram-negative bacterium
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide
GO:0070062 extracellular exosome
GO:0071222 cellular response to lipopolysaccharide

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
BPIPRSS2HPRD11420435 details
BPICD177UniProt21193407 details
BPICITBioGRID31586073 details