Entity Details

Primary name STAT5B
Entity type gene
Source Source Link

Details

PrimaryID6777
RefseqGeneNG_007271
SymbolSTAT5B
Namesignal transducer and activator of transcription 5B
Chromosome17
Location17q21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-20
ModificationDate2021-06-19

Ontological Relatives

UniProt IDsSTA5B_HUMAN

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001553 luteinization
GO:0001779 natural killer cell differentiation
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006952 defense response
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0007565 female pregnancy
GO:0007595 lactation
GO:0019218 regulation of steroid metabolic process
GO:0019221 cytokine-mediated signaling pathway
GO:0019530 taurine metabolic process
GO:0019915 lipid storage
GO:0030856 regulation of epithelial cell differentiation
GO:0032355 response to estradiol
GO:0032743 positive regulation of interleukin-2 production
GO:0032819 positive regulation of natural killer cell proliferation
GO:0032825 positive regulation of natural killer cell differentiation
GO:0032870 cellular response to hormone stimulus
GO:0033077 T cell differentiation in thymus
GO:0035259 glucocorticoid receptor binding
GO:0035723 interleukin-15-mediated signaling pathway
GO:0038110 interleukin-2-mediated signaling pathway
GO:0038111 interleukin-7-mediated signaling pathway
GO:0038113 interleukin-9-mediated signaling pathway
GO:0040014 regulation of multicellular organism growth
GO:0040018 positive regulation of multicellular organism growth
GO:0042104 positive regulation of activated T cell proliferation
GO:0042127 regulation of cell population proliferation
GO:0042448 progesterone metabolic process
GO:0042802 identical protein binding
GO:0043029 T cell homeostasis
GO:0043066 negative regulation of apoptotic process
GO:0043434 response to peptide hormone
GO:0045579 positive regulation of B cell differentiation
GO:0045588 positive regulation of gamma-delta T cell differentiation
GO:0045647 negative regulation of erythrocyte differentiation
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045931 positive regulation of mitotic cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
GO:0046543 development of secondary female sexual characteristics
GO:0046544 development of secondary male sexual characteristics
GO:0046983 protein dimerization activity
GO:0048541 Peyer's patch development
GO:0050729 positive regulation of inflammatory response
GO:0060397 growth hormone receptor signaling pathway via JAK-STAT
GO:0070670 response to interleukin-4
GO:0071363 cellular response to growth factor stimulus
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0097531 mast cell migration

Diseases

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Interactions

104 interactions

InteractorPartnerSourcesPublicationsLink
STAT5BNMIBioGRID, HPRD, IntAct9989503 details
STAT5BPTPN1BioGRID, HPRD, MINT12237455 details
STAT5BIL2RBBioGRID, HPRD, MINT10602027 details
STAT5BINSRBioGRID, HPRD, MINT10830280 12456798 9122188 9428692 details
STAT5BIL15BioGRID, IntAct21988832 details
STAT5BTFGBioGRID, IntAct21988832 details
STAT5BHAX1BioGRID, IntAct21988832 details
STAT5BSERTAD1BioGRID, IntAct21988832 details
STAT5BAFTPHBioGRID, IntAct21988832 details
STAT5BDMRTA1BioGRID, IntAct21988832 details
STAT5BGHRBioGRID, HPRD, IntAct25241761 8923468 details
STAT5BCTLA4BioGRID, HPRD, IntAct16476059 25241761 details
STAT5BZNF410IntAct32296183 details
STAT5BLGALS14BioGRID, IntAct32296183 details
STAT5BUSP2BioGRID, IntAct32296183 details
STAT5BCHAF1ABioGRID, IntAct32296183 details
STAT5BMED25BioGRID, IntAct32296183 details
STAT5BSTACBioGRID, IntAct32296183 details
STAT5BPIK3R3BioGRID, IntAct32296183 details
STAT5BTSSK3BioGRID, IntAct32296183 details
STAT5BCDKN1ABioGRID, IntAct32296183 details
STAT5BMRPS6BioGRID, IntAct32296183 details
STAT5BLMO4BioGRID, IntAct32296183 details
STAT5BRBBP4BioGRID, IntAct32296183 details
STAT5BSUOXBioGRID, IntAct32296183 details
STAT5BSTAT5BBioGRID, HPRD, IntAct12089361 14704793 20962278 22729867 31175292 details
STAT5BABL1IntAct31175292 details
STAT5BJAK2BioGRID, HPRD12538627 24354892 9047382 9575217 details
STAT5BPTPN11BioGRID, HPRD10617656 details
STAT5BJAK1BioGRID9047382 details
STAT5BJAK3BioGRID9047382 details
STAT5BELP2BioGRID, HPRD10954736 details
STAT5BAPPBioGRID21832049 details
STAT5BKITBioGRID, HPRD10358045 17554063 details
STAT5BHNRNPA2B1BioGRID32296183 details
STAT5BNCOR2HPRD11726519 details
STAT5BCENPJHPRD12198240 details
STAT5BEPORHPRD15644415 8977232 details
STAT5BSTAP2HPRD, MINT15611091 details
STAT5BEGFRBioGRID, HPRD, MINT10558875 11751923 16729043 22729867 details
STAT5BERBB4HPRD, MINT16729043 details
STAT5BDNAJA3IntAct21106534 details
STAT5BSTAT3BioGRID, HPRD, IntAct25241761 9398404 details
STAT5BIL2RAHPRD, IntAct10602027 11485747 details
STAT5BSTAT5ABioGRID, HPRD, IntAct28514442 9528750 details
STAT5BEPHA4IntAct31413325 details
STAT5BNR3C1BioGRID, HPRD11158330 8878484 9528750 details
STAT5BSHC1BioGRID, HPRD10996427 details
STAT5BCD247BioGRID, HPRD9880255 details
STAT5BCCR5BioGRID11350939 details
STAT5BPTPN6BioGRID, HPRD9211920 details
STAT5BPOU2F1BioGRID, HPRD14645506 16025120 details
STAT5BFGFR2BioGRID21464042 details
STAT5BPGRBioGRID21464042 details
STAT5BPRLRBioGRID20962278 details
STAT5BMAPK1HPRD10996427 details
STAT5BSRCHPRD12621061 details
STAT5BPTPN2HPRD11773439 15588985 details
STAT5BRARAHPRD11929748 details
STAT5BEP300HPRD14726487 9989503 details
STAT5BTEKHPRD14726409 details
STAT5BCXCR4HPRD10506573 details
STAT5BIL7RHPRD7719938 details
STAT5BCRKHPRD10720694 11097834 9845531 details
STAT5BCBLHPRD12193575 details
STAT5BPDGFRBHPRD9484840 details
STAT5BPDGFRAHPRD9484840 details
STAT5BSTAT1HPRD10358045 details
STAT5BCRKLHPRD10720694 11097834 9845531 details
STAT5BPPP2CAHPRD11440634 details
STAT5BETS1HPRD10815800 details
STAT5BETS2HPRD10815800 details
STAT5BCREBBPIntAct9989503 details
STAT5BVCAM1BioGRID, IntAct19738201 22623428 details
STAT5BDLATBioGRID, IntAct26496610 details
STAT5BPDHXBioGRID, IntAct26496610 details
STAT5BMVPBioGRID, IntAct26496610 details
STAT5BKANSL3BioGRID, IntAct26496610 details
STAT5BASF1BBioGRID, IntAct26496610 details
STAT5BPDHA1BioGRID, IntAct26496610 details
STAT5BDLDBioGRID, IntAct26496610 details
STAT5BPDHBBioGRID, IntAct26496610 details
STAT5BHIVEP1BioGRID, IntAct26496610 details
STAT5BPUS7LBioGRID, IntAct26496610 details
STAT5BADAM32BioGRID, IntAct28514442 details
STAT5BTRMOBioGRID, IntAct28514442 details
STAT5BDDR1MINT22057045 details
STAT5BRMC1BioGRID22939629 details
STAT5BAARS1BioGRID22863883 details
STAT5BANKMY2BioGRID22863883 details
STAT5BNIF3L1BioGRID22863883 details
STAT5BRPRD1ABioGRID22863883 details
STAT5BDPP9BioGRID22863883 details
STAT5BRPRD1BBioGRID22863883 details
STAT5BSURF2BioGRID22863883 details
STAT5BTOM1L1BioGRID22863883 details
STAT5BMCMBPBioGRID26344197 details
STAT5BALADBioGRID26344197 details
STAT5BNTRK1BioGRID25921289 details
STAT5BSOCS2BioGRID28883622 details
STAT5BKDM6BBioGRID30224337 details
STAT5BFOSL2IntAct24587342 details
STAT5BTRIM25BioGRID29117863 details
STAT5BHNRNPLBioGRID28611215 details