Entity Details

Primary name TFAP2B
Entity type gene
Source Source Link

Details

PrimaryID7021
RefseqGeneNG_008438
SymbolTFAP2B
Nametranscription factor AP-2 beta
Chromosome6
Location6p12.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAP2B_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001822 kidney development
GO:0003091 renal water homeostasis
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006006 glucose metabolic process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0010842 retina layer formation
GO:0010960 magnesium ion homeostasis
GO:0030510 regulation of BMP signaling pathway
GO:0035136 forelimb morphogenesis
GO:0035137 hindlimb morphogenesis
GO:0035810 positive regulation of urine volume
GO:0035909 aorta morphogenesis
GO:0042127 regulation of cell population proliferation
GO:0042493 response to drug
GO:0042593 glucose homeostasis
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0043588 skin development
GO:0045444 fat cell differentiation
GO:0045595 regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0048485 sympathetic nervous system development
GO:0048856 anatomical structure development
GO:0050796 regulation of insulin secretion
GO:0055062 phosphate ion homeostasis
GO:0055074 calcium ion homeostasis
GO:0055075 potassium ion homeostasis
GO:0055078 sodium ion homeostasis
GO:0072017 distal tubule development
GO:0072044 collecting duct development
GO:0072210 metanephric nephron development
GO:0097070 ductus arteriosus closure
GO:0097275 cellular ammonium homeostasis
GO:0097276 cellular creatinine homeostasis
GO:0097277 cellular urea homeostasis
GO:1990837 sequence-specific double-stranded DNA binding

Diseases

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Interactions

46 interactions

InteractorPartnerSourcesPublicationsLink
TFAP2BH2AC6HPRD, IntAct16169070 details
TFAP2BVPS11HPRD, IntAct16169070 details
TFAP2BUBE2IBioGRID, HPRD, IntAct12072434 details
TFAP2BCITED2BioGRID, IntAct11744733 12586840 details
TFAP2BYWHAGIntAct32814053 details
TFAP2BSETDB1IntAct32814053 details
TFAP2BKAT5IntAct32814053 details
TFAP2BLMO3IntAct32814053 details
TFAP2BSSBP4BioGRID, IntAct20211142 details
TFAP2BLZTR1BioGRID, IntAct20211142 details
TFAP2BCITED4BioGRID, HPRD11744733 details
TFAP2BCITED1BioGRID11744733 details
TFAP2BYEATS4BioGRID, HPRD16698963 details
TFAP2BAURKABioGRID28218735 details
TFAP2BKCTD1BioGRID19115315 details
TFAP2BTP53BioGRID20159018 details
TFAP2BCREBBPBioGRID25294805 details
TFAP2BTFAP2ABioGRID18843039 details
TFAP2BMEGF10BioGRID17643423 details
TFAP2BMYCHPRD7729426 details
TFAP2BSYT4HPRD7993622 details
TFAP2BESR2BioGRID29509190 details
TFAP2BCCL11IntAct33179750 details
TFAP2BCCL27IntAct33179750 details
TFAP2BCCL28IntAct33179750 details
TFAP2BCCL4L2IntAct33179750 details
TFAP2BCCL4IntAct33179750 details
TFAP2BCCL5IntAct33179750 details
TFAP2BCX3CL1IntAct33179750 details
TFAP2BCSF2IntAct33179750 details
TFAP2BCXCL8IntAct33179750 details
TFAP2BIL15IntAct33179750 details
TFAP2BIL12BIntAct33179750 details
TFAP2BIL17BIntAct33179750 details
TFAP2BIL18IntAct33179750 details
TFAP2BIL20IntAct33179750 details
TFAP2BIL22IntAct33179750 details
TFAP2BIL3IntAct33179750 details
TFAP2BIL32IntAct33179750 details
TFAP2BIL37IntAct33179750 details
TFAP2BKITLGIntAct33179750 details
TFAP2BOSMIntAct33179750 details
TFAP2BPPBPIntAct33179750 details
TFAP2BTNFIntAct33179750 details
TFAP2BTNFSF13IntAct33179750 details
TFAP2BTNFSF9IntAct33179750 details