Entity Details

Primary name TIGIT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ495A1
EntryNameTIGIT_HUMAN
FullNameT-cell immunoreceptor with Ig and ITIM domains
TaxID9606
Evidenceevidence at protein level
Length244
SequenceStatuscomplete
DateCreated2007-09-11
DateModified2021-06-02

Ontological Relatives

GenesTIGIT

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0032695 negative regulation of interleukin-12 production
GO:0032733 positive regulation of interleukin-10 production
GO:0042802 identical protein binding
GO:0050868 negative regulation of T cell activation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR042948 T-cell immunoglobulin and ITIM domain receptorFamilyFamily

Diseases

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