Entity Details

Primary name DDR1
Entity type gene
Source Source Link

Details

PrimaryID780
RefseqGeneNG_029066
SymbolDDR1
Namediscoidin domain receptor tyrosine kinase 1
Chromosome6
Location6p21.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-07-13
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsDDR1_HUMAN

GO terms

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GOName
GO:0001558 regulation of cell growth
GO:0001952 regulation of cell-matrix adhesion
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005518 collagen binding
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007155 cell adhesion
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007275 multicellular organism development
GO:0007566 embryo implantation
GO:0007595 lactation
GO:0008285 negative regulation of cell population proliferation
GO:0010715 regulation of extracellular matrix disassembly
GO:0014909 smooth muscle cell migration
GO:0030198 extracellular matrix organization
GO:0033674 positive regulation of kinase activity
GO:0038062 protein tyrosine kinase collagen receptor activity
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway
GO:0038083 peptidyl-tyrosine autophosphorylation
GO:0043235 receptor complex
GO:0043583 ear development
GO:0044319 wound healing, spreading of cells
GO:0046777 protein autophosphorylation
GO:0046872 metal ion binding
GO:0060444 branching involved in mammary gland duct morphogenesis
GO:0060749 mammary gland alveolus development
GO:0061302 smooth muscle cell-matrix adhesion
GO:0061564 axon development
GO:0070062 extracellular exosome
GO:1990138 neuron projection extension

Diseases

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Interactions

82 interactions

InteractorPartnerSourcesPublicationsLink
DDR1SNAPINBioGRID, HPRD, IntAct16169070 details
DDR1TTRBioGRID, HPRD, IntAct16169070 details
DDR1RGS2BioGRID, HPRD, IntAct, MINT16169070 21900206 details
DDR1TM4SF1BioGRID, HPRD, IntAct16169070 details
DDR1SNRNP40BioGRID, HPRD, IntAct16169070 details
DDR1BEND5HPRD, IntAct16169070 details
DDR1PTPN11HPRD, MINT16337946 22057045 details
DDR1NCK2HPRD, MINT16337946 22057045 details
DDR1IRS1IntAct17721511 details
DDR1MAPK6BioGRID, MINT21900206 details
DDR1NUDT3BioGRID, MINT21900206 details
DDR1UBQLN2BioGRID, IntAct32296183 details
DDR1COL3A1DIP, HPRD22483115 9659900 details
DDR1SHC1BioGRID, HPRD, MINT10783152 22057045 9659899 details
DDR1ERBB2BioGRID30898150 details
DDR1PLCG1HPRD, MINT10783152 22057045 details
DDR1DDR1HPRD, MINT22057045 9659899 details
DDR1CDH1BioGRID20432435 details
DDR1CDH2BioGRID20432435 details
DDR1FRS2HPRD10783152 details
DDR1COL2A1HPRD9659900 details
DDR1COL5A2HPRD9659900 details
DDR1COL11A1HPRD9659900 details
DDR1CDC37BioGRID, IntAct, MINT22057045 24189400 details
DDR1TNFRSF10BBioGRID, IntAct28514442 details
DDR1RASA1MINT22057045 details
DDR1CRKMINT22057045 details
DDR1VAV3MINT22057045 details
DDR1INPPL1MINT22057045 details
DDR1VAV2MINT22057045 details
DDR1TLN1MINT22057045 details
DDR1INPP5DMINT22057045 details
DDR1CSKMINT22057045 details
DDR1EZRMINT22057045 details
DDR1STAT5BMINT22057045 details
DDR1PIK3R1MINT22057045 details
DDR1PALLDMINT22057045 details
DDR1YES1MINT22057045 details
DDR1LYNMINT22057045 details
DDR1PIK3R2MINT22057045 details
DDR1PIK3CBMINT22057045 details
DDR1STAT3MINT22057045 details
DDR1PIK3CDMINT22057045 details
DDR1PIK3CAMINT22057045 details
DDR1STAT1MINT22057045 details
DDR1PIK3R3MINT22057045 details
DDR1SRCMINT22057045 details
DDR1FYNMINT22057045 details
DDR1NCK1MINT22057045 details
DDR1VDAC3MINT22057045 details
DDR1ITCHMINT22057045 details
DDR1UBASH3BMINT22057045 details
DDR1IMMTMINT22057045 details
DDR1TRIP13MINT22057045 details
DDR1BRD3MINT22057045 details
DDR1NOLC1MINT22057045 details
DDR1FLNCMINT22057045 details
DDR1CALD1MINT22057045 details
DDR1BASP1MINT22057045 details
DDR1GRB2MINT22057045 details
DDR1NAP1L1MINT22057045 details
DDR1RANGAP1MINT22057045 details
DDR1VDAC2MINT22057045 details
DDR1NF2MINT22057045 details
DDR1EPHA2MINT22057045 details
DDR1BRD2MINT22057045 details
DDR1NT5EMINT22057045 details
DDR1ACO1MINT22057045 details
DDR1FDPSMINT22057045 details
DDR1PFN1MINT22057045 details
DDR1THY1MINT22057045 details
DDR1TFRCMINT22057045 details
DDR1PNPMINT22057045 details
DDR1ZRANB2MINT22057045 details
DDR1CSMINT22057045 details
DDR1ORC5MINT22057045 details
DDR1DCTN1MINT22057045 details
DDR1HSP90AA1BioGRID22939624 details
DDR1VIRMABioGRID29507755 details
DDR1MOV10BioGRID22658674 details
DDR1NXF1BioGRID22658674 details
DDR1HNRNPLBioGRID28611215 details