Entity Details

Primary name NELFE
Entity type gene
Source Source Link

Details

PrimaryID7936
RefseqGene
SymbolNELFE
Namenegative elongation factor complex member E
Chromosome6
Location6p21.33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsNELFE_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003682 chromatin binding
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0006366 transcription by RNA polymerase II
GO:0006368 transcription elongation from RNA polymerase II promoter
GO:0016604 nuclear body
GO:0032021 NELF complex
GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050434 positive regulation of viral transcription
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:1900364 negative regulation of mRNA polyadenylation

Diseases

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Interactions

55 interactions

InteractorPartnerSourcesPublicationsLink
NELFENELFBBioGRID, HPRD, IntAct, MINT, UniProt10199401 12612062 14667819 15342491 20211142 20305087 24981860 26186194 26496610 28514442 32296183 details
NELFENCOR1BioGRID, HPRD, IntAct14667819 details
NELFEVAMP3BioGRID, HPRD, IntAct16169070 details
NELFENELFABioGRID, IntAct, MINT, UniProt12612062 20305087 24981860 26186194 26496610 28514442 details
NELFENELFCDBioGRID, IntAct, MINT, UniProt12612062 17353931 20305087 24981860 26186194 26496610 28514442 details
NELFESRPK2BioGRID, IntAct23602568 details
NELFESRPK1BioGRID, IntAct23602568 details
NELFETRIM27BioGRID, IntAct25416956 details
NELFECCDC57BioGRID, IntAct25416956 details
NELFEMTUS2BioGRID, IntAct25416956 details
NELFEKANK2IntAct32296183 details
NELFECACTINBioGRID14667819 details
NELFETNKSBioGRID29604130 details
NELFEYWHAGIntAct17353931 details
NELFEHSP90AB1IntAct22579285 details
NELFEPOLR2ABioGRID12612062 details
NELFESF3B1BioGRID20305087 details
NELFETMEM141BioGRID20305087 details
NELFENELFEHPRD10199401 12612062 details
NELFEWDR48BioGRID, IntAct19615732 details
NELFENCBP1BioGRID, IntAct26496610 32960270 details
NELFENCBP2BioGRID, IntAct26382858 26496610 32960270 details
NELFEFECHBioGRID, IntAct28514442 details
NELFEDIS3BioGRID, IntAct26186194 28514442 details
NELFEIGHMBP2BioGRID, IntAct26186194 28514442 details
NELFEPOLR2CBioGRID, DIP18562274 details
NELFEH1-2BioGRID, MINT24981860 details
NELFEFABP5BioGRID, MINT24981860 details
NELFELORICRINBioGRID, MINT24981860 details
NELFEC1orf68BioGRID, MINT24981860 details
NELFEPRSS3BioGRID, MINT24981860 details
NELFESRSF1BioGRID, MINT24981860 details
NELFERPAP2BioGRID17643375 details
NELFELMNABioGRID22412018 details
NELFETTC29BioGRID26186194 details
NELFEPSMA1BioGRID26344197 details
NELFEPSMA3BioGRID26344197 details
NELFEPSMA5BioGRID26344197 details
NELFEPSMA6BioGRID26344197 details
NELFEPSMB4BioGRID26344197 details
NELFEPSMB6BioGRID26344197 details
NELFEPYM1BioGRID26344197 details
NELFENTRK1BioGRID25921289 details
NELFERSRC1BioGRID26496610 details
NELFEEFTUD2BioGRID28515276 details
NELFEATG16L1BioGRID30196744 details
NELFEACTC1BioGRID30890647 details
NELFEXRCC6BioGRID30585729 details
NELFESNRNP70BioGRID29802200 details
NELFEWWP2BioGRID31048545 details
NELFEPLEKHA4BioGRID31091453 details
NELFEBCAR1BioGRID33001583 details
NELFEBRD4BioGRID32416067 details
NELFEWDR76BioGRID31353912 details
NELFETERF2IPBioGRID34079125 details