Entity Details

Primary name LGR5
Entity type gene
Source Source Link

Details

PrimaryID8549
RefseqGene
SymbolLGR5
Nameleucine rich repeat containing G protein-coupled receptor 5
Chromosome12
Location12q21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-10-07
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsLGR5_HUMAN

GO terms

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GOName
GO:0001942 hair follicle development
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0005654 nucleoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0008528 G protein-coupled peptide receptor activity
GO:0009755 hormone-mediated signaling pathway
GO:0009994 oocyte differentiation
GO:0016500 protein-hormone receptor activity
GO:0032588 trans-Golgi network membrane
GO:0042127 regulation of cell population proliferation
GO:0048839 inner ear development
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
LGR5RSPO2BioGRID29769720 details
LGR5ZNRF3BioGRID26123262 details
LGR5APPUniProt30664241 details
LGR5NTRK1BioGRID25921289 details