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Entity Details
Primary name
TOP3B
Entity type
gene
Source
Source Link
Details
PrimaryID
8940
RefseqGene
Symbol
TOP3B
Name
DNA topoisomerase III beta
Chromosome
22
Location
22q11.22
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
1999-06-16
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
TOP3B_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0000793
condensed chromosome
GO:0003677
DNA binding
GO:0003723
RNA binding
GO:0003916
DNA topoisomerase activity
GO:0003917
DNA topoisomerase type I (single strand cut, ATP-independent) activity
GO:0005634
nucleus
GO:0006265
DNA topological change
GO:0007059
chromosome segregation
Diseases
Show/Hide Table
Interactions
172 interactions
Interactor
Partner
Sources
Publications
Link
TOP3B
ZNF408
BioGRID, HPRD, IntAct
15231747
details
TOP3B
CHIC2
BioGRID, HPRD, IntAct
16189514
details
TOP3B
KRTAP4-12
BioGRID, HPRD, IntAct
16189514
31515488
details
TOP3B
ADAMTSL4
BioGRID, IntAct
25416956
31515488
details
TOP3B
SPRED2
BioGRID, IntAct
25416956
29892012
details
TOP3B
TRIM41
BioGRID, IntAct
25416956
31515488
details
TOP3B
MID2
BioGRID, IntAct
25416956
31515488
32296183
details
TOP3B
PNMA2
BioGRID, IntAct
25416956
details
TOP3B
SSX2IP
BioGRID, IntAct
25416956
31515488
details
TOP3B
BHLHB9
BioGRID, IntAct
32296183
details
TOP3B
ZNF250
BioGRID, IntAct
32296183
details
TOP3B
KANK2
BioGRID, IntAct
32296183
details
TOP3B
AXIN2
BioGRID, IntAct
32296183
details
TOP3B
FASTK
BioGRID, IntAct
32296183
details
TOP3B
CIAO1
BioGRID, IntAct
32296183
details
TOP3B
TDRD3
BioGRID, MINT, UniProt
24981860
26344197
28101374
28176834
29395067
details
TOP3B
SNRPB
BioGRID, HPRD
11549288
details
TOP3B
CENPF
BioGRID, HPRD
11549288
details
TOP3B
CHD8
BioGRID, HPRD
11549288
details
TOP3B
FBLN5
BioGRID, HPRD
11549288
details
TOP3B
GRN
BioGRID, HPRD
11549288
details
TOP3B
UPF2
BioGRID
15231747
details
TOP3B
C1QBP
HPRD
11549288
details
TOP3B
ZFPM1
HPRD
15231747
details
TOP3B
PTGES3L
IntAct
25036637
details
TOP3B
PTGES3L-AARSD1
IntAct
25036637
details
TOP3B
AARSD1
IntAct
25036637
details
TOP3B
RECQL5
BioGRID, HPRD
10710432
details
TOP3B
MMS19
BioGRID
22678362
29395067
details
TOP3B
MIB1
BioGRID
24239288
31462741
details
TOP3B
ZC3H7A
BioGRID
29395067
30995489
details
TOP3B
FMR1
BioGRID
29395067
details
TOP3B
IGF2BP2
BioGRID
29395067
details
TOP3B
KIF1B
BioGRID
29395067
details
TOP3B
LARP4B
BioGRID
29395067
details
TOP3B
MEX3B
BioGRID
29395067
details
TOP3B
MKRN2
BioGRID
29395067
details
TOP3B
MOV10
BioGRID
29395067
details
TOP3B
NUFIP2
BioGRID
29395067
details
TOP3B
OTUD4
BioGRID
29395067
details
TOP3B
PABPC1
BioGRID
29395067
details
TOP3B
PAIP1
BioGRID
29395067
details
TOP3B
PAIP2
BioGRID
29395067
details
TOP3B
PATL1
BioGRID
29395067
details
TOP3B
PRRC2A
BioGRID
29395067
details
TOP3B
PUM1
BioGRID
29395067
details
TOP3B
R3HDM2
BioGRID
29395067
details
TOP3B
RBM47
BioGRID
29395067
details
TOP3B
RBMS1
BioGRID
29395067
details
TOP3B
SAMD4B
BioGRID
29395067
details
TOP3B
SMAP2
BioGRID
29395067
details
TOP3B
SMG6
BioGRID
29395067
details
TOP3B
STAU1
BioGRID
29395067
details
TOP3B
SYNCRIP
BioGRID
29395067
details
TOP3B
CDKAL1
BioGRID
29395067
details
TOP3B
DNAJA1
BioGRID
29395067
details
TOP3B
DNAJA2
BioGRID
29395067
details
TOP3B
RPS10
BioGRID
29395067
details
TOP3B
SND1
BioGRID
29395067
details
TOP3B
UNC45A
BioGRID
29395067
details
TOP3B
TRIM25
BioGRID
29395067
details
TOP3B
TRIM56
BioGRID
29395067
details
TOP3B
UBAP2L
BioGRID
29395067
details
TOP3B
UNK
BioGRID
29395067
details
TOP3B
USP10
BioGRID
29395067
details
TOP3B
XRN1
BioGRID
29395067
details
TOP3B
YTHDF1
BioGRID
29395067
details
TOP3B
YTHDF2
BioGRID
29395067
details
TOP3B
YTHDF3
BioGRID
29395067
details
TOP3B
ZC3HAV1
BioGRID
29395067
details
TOP3B
ZFP36
BioGRID
29395067
details
TOP3B
CNOT7
BioGRID
29395067
details
TOP3B
DDX20
BioGRID
29395067
details
TOP3B
PRRC2B
BioGRID
29395067
details
TOP3B
STRAP
BioGRID
29395067
details
TOP3B
TIA1
BioGRID
29395067
details
TOP3B
BYSL
BioGRID
29395067
details
TOP3B
LARP4
BioGRID
29395067
details
TOP3B
UPF1
BioGRID
29395067
details
TOP3B
ZZEF1
BioGRID
29395067
details
TOP3B
CNOT6L
BioGRID
29395067
details
TOP3B
DDX19B
BioGRID
29395067
details
TOP3B
ZNF598
BioGRID
29395067
details
TOP3B
RC3H2
BioGRID
29395067
details
TOP3B
SMG7
BioGRID
29395067
details
TOP3B
TNRC6B
BioGRID
29395067
details
TOP3B
DHX57
BioGRID
29395067
details
TOP3B
RTEL1
BioGRID
29395067
details
TOP3B
SECISBP2
BioGRID
29395067
details
TOP3B
THOC2
BioGRID, IntAct
26496610
details
TOP3B
THOC1
BioGRID, IntAct
26496610
details
TOP3B
RPL10
BioGRID, IntAct
26496610
details
TOP3B
ATP6AP2
BioGRID, IntAct
26496610
details
TOP3B
TSNAX
BioGRID, IntAct
26496610
details
TOP3B
RPA1
BioGRID, IntAct
26496610
details
TOP3B
GBA
BioGRID, IntAct
26496610
details
TOP3B
NUDT21
BioGRID, IntAct
26496610
details
TOP3B
POC1A
BioGRID, IntAct
26638075
details
TOP3B
RCC1
BioGRID, MINT
24981860
details
TOP3B
SUB1
BioGRID, MINT
24981860
details
TOP3B
SNRNP40
BioGRID, MINT
24981860
details
TOP3B
RBMX2
BioGRID, MINT
24981860
details
TOP3B
TAF15
BioGRID, MINT
24981860
details
TOP3B
CBX5
BioGRID, MINT
24981860
details
TOP3B
NOP2
BioGRID, MINT
24981860
details
TOP3B
LYAR
BioGRID, MINT
24981860
details
TOP3B
RPL22
BioGRID, MINT
24981860
details
TOP3B
H2BC11
BioGRID, MINT
24981860
details
TOP3B
HMGN2
BioGRID, MINT
24981860
details
TOP3B
PSIP1
BioGRID, MINT
24981860
details
TOP3B
POLDIP3
BioGRID, MINT
24981860
details
TOP3B
HMGN1
BioGRID, MINT
24981860
details
TOP3B
H3C1
BioGRID, MINT
24981860
details
TOP3B
H3C4
MINT
24981860
details
TOP3B
H3C3
MINT
24981860
details
TOP3B
H3C6
MINT
24981860
details
TOP3B
H3C11
MINT
24981860
details
TOP3B
H3C8
MINT
24981860
details
TOP3B
H3C12
MINT
24981860
details
TOP3B
H3C10
MINT
24981860
details
TOP3B
H3C2
MINT
24981860
details
TOP3B
H3C7
MINT
24981860
details
TOP3B
H3-3A
BioGRID, MINT
24981860
details
TOP3B
H3-3B
MINT
24981860
details
TOP3B
MACROH2A1
BioGRID, MINT
24981860
details
TOP3B
HMGN4
BioGRID, MINT
24981860
details
TOP3B
H2AC21
BioGRID, MINT
24981860
details
TOP3B
H2BC5
BioGRID, MINT
24981860
details
TOP3B
FXR1
BioGRID
24778252
29395067
details
TOP3B
CIAO2A
BioGRID
23891004
details
TOP3B
CIAO2B
BioGRID
23891004
details
TOP3B
FOXL1
BioGRID
25609649
details
TOP3B
CDC14A
BioGRID
27880917
details
TOP3B
PLEKHA4
BioGRID
31091453
details
TOP3B
AGO2
BioGRID
29395067
details
TOP3B
ANKRD17
BioGRID
29395067
details
TOP3B
ATXN2
BioGRID
29395067
details
TOP3B
CAPRIN1
BioGRID
29395067
details
TOP3B
CELF1
BioGRID
29395067
details
TOP3B
CNOT2
BioGRID
29395067
details
TOP3B
CPEB4
BioGRID
29395067
details
TOP3B
CSDE1
BioGRID
29395067
details
TOP3B
CTIF
BioGRID
29395067
details
TOP3B
DAZL
BioGRID
29395067
details
TOP3B
DDX3X
BioGRID
29395067
details
TOP3B
DDX6
BioGRID
29395067
details
TOP3B
EIF4A1
BioGRID
29395067
details
TOP3B
EIF4A2
BioGRID
29395067
details
TOP3B
EIF4ENIF1
BioGRID
29395067
details
TOP3B
ELAVL1
BioGRID
29395067
details
TOP3B
FAM120A
BioGRID
29395067
details
TOP3B
FAM120C
BioGRID
29395067
details
TOP3B
FUBP3
BioGRID
29395067
details
TOP3B
FXR2
BioGRID
29395067
details
TOP3B
G3BP1
BioGRID
29395067
details
TOP3B
GRSF1
BioGRID
29395067
32877691
details
TOP3B
GTPBP1
BioGRID
29395067
details
TOP3B
HDLBP
BioGRID
29395067
details
TOP3B
HELZ
BioGRID
29395067
details
TOP3B
IBTK
BioGRID
29395067
details
TOP3B
IGF2BP1
BioGRID
29395067
details
TOP3B
LSM12
BioGRID
29395067
details
TOP3B
LSM14A
BioGRID
29395067
details
TOP3B
LSM4
BioGRID
29395067
details
TOP3B
LRRC31
BioGRID
33005030
details
TOP3B
DDX28
BioGRID
32877691
details
TOP3B
DHX30
BioGRID
32877691
details
TOP3B
PRKACA
BioGRID
33957083
details
TOP3B
DDRGK1
BioGRID
32807901
details
TOP3B
TP53
BioGRID
32807901
details
TOP3B
FBL
BioGRID
34079125
details
TOP3B
RPS20
BioGRID
34079125
details
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