Entity Details

Primary name ACVR2B
Entity type gene
Source Source Link

Details

PrimaryID93
RefseqGeneNG_011791
SymbolACVR2B
Nameactivin A receptor type 2B
Chromosome3
Location3p22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-06-19
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAVR2B_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001946 lymphangiogenesis
GO:0001974 blood vessel remodeling
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0009952 anterior/posterior pattern specification
GO:0017002 activin-activated receptor activity
GO:0019838 growth factor binding
GO:0030501 positive regulation of bone mineralization
GO:0030509 BMP signaling pathway
GO:0030513 positive regulation of BMP signaling pathway
GO:0030514 negative regulation of BMP signaling pathway
GO:0032924 activin receptor signaling pathway
GO:0032927 positive regulation of activin receptor signaling pathway
GO:0032991 protein-containing complex
GO:0043235 receptor complex
GO:0045669 positive regulation of osteoblast differentiation
GO:0046872 metal ion binding
GO:0048179 activin receptor complex
GO:0048185 activin binding
GO:0060836 lymphatic endothelial cell differentiation
GO:0060840 artery development
GO:0060841 venous blood vessel development
GO:0061298 retina vasculature development in camera-type eye
GO:0071363 cellular response to growth factor stimulus
GO:0120163 negative regulation of cold-induced thermogenesis

Diseases

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Interactions

59 interactions

InteractorPartnerSourcesPublicationsLink
ACVR2BFSTL1MINT20860622 details
ACVR2BGDF11HPRD, MINT16845371 21054789 details
ACVR2BMSTNBioGRID, HPRD, MINT11459935 23829672 details
ACVR2BSYNJ2BPBioGRID, HPRD11882656 15451561 details
ACVR2BERBINBioGRID15123239 details
ACVR2BGDF2BioGRID22718755 details
ACVR2BBMP10BioGRID22718755 details
ACVR2BFBXO7BioGRID27503909 details
ACVR2BTDGF1BioGRID28126904 details
ACVR2BNODALBioGRID28126904 details
ACVR2BHSP90AB1IntAct22939624 details
ACVR2BACVR1BBioGRID, HPRD8612709 8622651 details
ACVR2BGDF5BioGRID, HPRD8702914 details
ACVR2BENGBioGRID9872992 details
ACVR2BINHBBBioGRID, HPRD9202237 details
ACVR2BINHBABioGRID, HPRD8242742 9202237 details
ACVR2BBMP6BioGRID10504300 details
ACVR2BBMP7BioGRID, HPRD9748228 details
ACVR2BSNX6BioGRID, HPRD11279102 details
ACVR2BSNX2BioGRID, HPRD11279102 details
ACVR2BSNX1BioGRID, HPRD11279102 details
ACVR2BIGSF1BioGRID, HPRD11266516 details
ACVR2BSMAD2BioGRID11094085 details
ACVR2BSMAD7BioGRID20663871 details
ACVR2BSMAD6BioGRID20663871 details
ACVR2BHSP90AA1BioGRID22939624 details
ACVR2BPEG10BioGRID15611116 details
ACVR2BRGMBBioGRID15671031 details
ACVR2BPSMD14BioGRID31685442 details
ACVR2BINHBCHPRD12651901 details
ACVR2BTGFBRAP1HPRD11278302 details
ACVR2BBMP2HPRD15064755 details
ACVR2BADGRG5BioGRID, IntAct28514442 details
ACVR2BMANSC1BioGRID, IntAct28514442 details
ACVR2BMAS1BioGRID, IntAct28514442 details
ACVR2BIZUMO1BioGRID, IntAct28514442 details
ACVR2BRUSF1BioGRID, IntAct28514442 details
ACVR2BDLK1BioGRID, IntAct26186194 28514442 details
ACVR2BKIR3DL2BioGRID, IntAct28514442 details
ACVR2BPCDHGB4BioGRID, IntAct28514442 details
ACVR2BZNRF4BioGRID, IntAct28514442 details
ACVR2BTMEM30ABioGRID, IntAct26186194 28514442 details
ACVR2BPTGER3BioGRID, IntAct26186194 28514442 details
ACVR2BGRPRBioGRID, IntAct28514442 details
ACVR2BLDLRAD4BioGRID, IntAct26186194 28514442 details
ACVR2BMRAP2BioGRID, IntAct28514442 details
ACVR2BTGFBR2BioGRID, IntAct26186194 28514442 details
ACVR2BCD79BBioGRID, IntAct28514442 details
ACVR2BCNGA3BioGRID, IntAct28514442 details
ACVR2BIL17RCBioGRID, IntAct28514442 details
ACVR2BPDGFRBBioGRID, IntAct28514442 details
ACVR2BPCDHGA5BioGRID, IntAct28514442 details
ACVR2BHEPACAM2BioGRID, IntAct28514442 details
ACVR2BLRRIQ1BioGRID, IntAct28514442 details
ACVR2BGINM1BioGRID, IntAct28514442 details
ACVR2BIL4RBioGRID, IntAct28514442 details
ACVR2BIL17RBBioGRID, IntAct28514442 details
ACVR2BHNRNPLBioGRID28611215 details
ACVR2BVIRMABioGRID29507755 details