Entity Details

Primary name BIG3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5TH69
EntryNameBIG3_HUMAN
FullNameBrefeldin A-inhibited guanine nucleotide-exchange protein 3
TaxID9606
Evidenceevidence at protein level
Length2177
SequenceStatuscomplete
DateCreated2007-05-15
DateModified2021-06-02

Ontological Relatives

GenesARFGEF3

GO terms

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GOName
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0010923 negative regulation of phosphatase activity
GO:0016021 integral component of membrane
GO:0030036 actin cytoskeleton organization
GO:0030658 transport vesicle membrane
GO:0032012 regulation of ARF protein signal transduction

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle

Domains

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DomainNameCategoryType
IPR000904 Sec7 domainDomainDomain
IPR015403 Sec7, C-terminalDomainDomain
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR032629 Mon2, dimerisation and cyclophilin-binding domainDomainDomain

Diseases

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