Entity Details

Primary name RNF43_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ68DV7
EntryNameRNF43_HUMAN
FullNameE3 ubiquitin-protein ligase RNF43
TaxID9606
Evidenceevidence at protein level
Length783
SequenceStatuscomplete
DateCreated2007-02-20
DateModified2021-06-02

Ontological Relatives

GenesRNF43

GO terms

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GOName
GO:0004842 ubiquitin-protein transferase activity
GO:0005109 frizzled binding
GO:0005635 nuclear envelope
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0007275 multicellular organism development
GO:0016055 Wnt signaling pathway
GO:0016567 protein ubiquitination
GO:0030178 negative regulation of Wnt signaling pathway
GO:0038018 Wnt receptor catabolic process
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
GO:0072089 stem cell proliferation

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum membrane
Nucleus envelope

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR040700 ZNRF-3, ectodomainDomainDomain

Diseases

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