Entity Details

Primary name NXN_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6DKJ4
EntryNameNXN_HUMAN
FullNameNucleoredoxin
TaxID9606
Evidenceevidence at protein level
Length435
SequenceStatuscomplete
DateCreated2008-04-29
DateModified2021-06-02

Ontological Relatives

GenesNXN

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0004791 thioredoxin-disulfide reductase activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0016055 Wnt signaling pathway
GO:0030154 cell differentiation
GO:0030178 negative regulation of Wnt signaling pathway
GO:0031397 negative regulation of protein ubiquitination
GO:0047134 protein-disulfide reductase (NAD(P)) activity
GO:0072359 circulatory system development

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR012336 Thioredoxin-like foldDomainDomain
IPR013766 Thioredoxin domainDomainDomain
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily
IPR041861 Nucleoredoxin, redox inactive TRX-like domain b'DomainDomain

Diseases

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