Entity Details

Primary name RGMC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6ZVN8
EntryNameRGMC_HUMAN
FullNameHemojuvelin
TaxID9606
Evidenceevidence at protein level
Length426
SequenceStatuscomplete
DateCreated2004-08-16
DateModified2021-06-02

Ontological Relatives

GenesHJV

GO terms

Show/Hide Table
GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0005102 signaling receptor binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0006879 cellular iron ion homeostasis
GO:0015026 coreceptor activity
GO:0016540 protein autoprocessing
GO:0030509 BMP signaling pathway
GO:0031225 anchored component of membrane
GO:0032924 activin receptor signaling pathway
GO:0036122 BMP binding
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0055072 iron ion homeostasis
GO:0070724 BMP receptor complex
GO:0071773 cellular response to BMP stimulus
GO:0098797 plasma membrane protein complex
GO:1990459 transferrin receptor binding
GO:1990712 HFE-transferrin receptor complex

Subcellular Location

Show/Hide Table
Subcellular Location
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR009496 Repulsive guidance molecule, C-terminalDomainDomain
IPR010536 Repulsive guidance molecule, N-terminalDomainDomain
IPR016123 Mog1/PsbP, alpha/beta/alpha sandwichFamilyHomologous superfamily
IPR033606 HemojuvelinFamilyFamily
IPR040287 Repulsive guidance moleculeFamilyFamily

Diseases

Show/Hide Table

Interactions

4 interactions