Entity Details

Primary name MEPCE_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7L2J0
EntryNameMEPCE_HUMAN
FullName7SK snRNA methylphosphate capping enzyme
TaxID9606
Evidenceevidence at protein level
Length689
SequenceStatuscomplete
DateCreated2007-05-29
DateModified2021-06-02

Ontological Relatives

GenesMEPCE

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001510 RNA methylation
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0008171 O-methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0016073 snRNA metabolic process
GO:0017069 snRNA binding
GO:0035562 negative regulation of chromatin binding
GO:0040031 snRNA modification
GO:0097322 7SK snRNA binding
GO:0120259 7SK snRNP
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:1904871 positive regulation of protein localization to Cajal body
GO:1905382 positive regulation of snRNA transcription by RNA polymerase II
GO:1990276 RNA 5'-methyltransferase activity
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR010675 RNA methyltransferase bin3, C-terminalDomainDomain
IPR024160 Bin3-type S-adenosyl-L-methionine binding domainDomainDomain
IPR025714 Methyltransferase domainDomainDomain
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily
IPR039772 RNA methyltransferase Bin3-likeFamilyFamily

Diseases

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