Entity Details

Primary name PTF1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ7RTS3
EntryNamePTF1A_HUMAN
FullNamePancreas transcription factor 1 subunit alpha
TaxID9606
Evidenceevidence at protein level
Length328
SequenceStatuscomplete
DateCreated2006-05-02
DateModified2021-06-02

Ontological Relatives

GenesPTF1A

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009888 tissue development
GO:0010842 retina layer formation
GO:0021549 cerebellum development
GO:0031016 pancreas development
GO:0031017 exocrine pancreas development
GO:0032502 developmental process
GO:0035881 amacrine cell differentiation
GO:0046983 protein dimerization activity
GO:0048384 retinoic acid receptor signaling pathway
GO:0048663 neuron fate commitment
GO:0061074 regulation of neural retina development
GO:0070888 E-box binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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