Entity Details

Primary name MIB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86YT6
EntryNameMIB1_HUMAN
FullNameE3 ubiquitin-protein ligase MIB1
TaxID9606
Evidenceevidence at protein level
Length1006
SequenceStatuscomplete
DateCreated2005-07-05
DateModified2021-06-02

Ontological Relatives

GenesMIB1

GO terms

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GOName
GO:0001568 blood vessel development
GO:0001701 in utero embryonic development
GO:0001756 somitogenesis
GO:0001841 neural tube formation
GO:0001947 heart looping
GO:0004842 ubiquitin-protein transferase activity
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006897 endocytosis
GO:0007219 Notch signaling pathway
GO:0008270 zinc ion binding
GO:0014069 postsynaptic density
GO:0016567 protein ubiquitination
GO:0031410 cytoplasmic vesicle
GO:0045665 negative regulation of neuron differentiation
GO:0045807 positive regulation of endocytosis

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000433 Zinc finger, ZZ-typeDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR010606 Mib-herc2DomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily
IPR037252 Mib/herc2 domain superfamilyFamilyHomologous superfamily
IPR040847 Mind bomb, SH3 repeat domainDomainDomain
IPR042056 E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-typeDomainDomain
IPR043145 Zinc finger, ZZ-type superfamilyFamilyHomologous superfamily

Diseases

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Interactions

45 interactions

InteractorPartnerSourcesPublicationsLink
MIB1_HUMANSNX5_HUMANBioGRID, HPRD, MINT16857196 details
MIB1_HUMANUB2D1_HUMANBioGRID, IntAct19690564 details
MIB1_HUMANUB2D2_HUMANBioGRID, IntAct19690564 25747658 details
MIB1_HUMANUB2D3_HUMANBioGRID, IntAct19690564 24239288 details
MIB1_HUMANUB2D4_HUMANBioGRID, IntAct19690564 details
MIB1_HUMANUBE2N_HUMANBioGRID, IntAct19690564 21903422 details
MIB1_HUMANUBE2U_HUMANBioGRID, IntAct19690564 details
MIB1_HUMANUBE2W_HUMANBioGRID, IntAct19690564 details
MIB1_HUMANTBK1_HUMANBioGRID, IntAct21903422 31462741 details
MIB1_HUMANGBRAP_HUMANBioGRID, IntAct28712572 details
MIB1_HUMANJAG1_HUMANBioGRID20720151 25747658 details
MIB1_HUMANAZI2_HUMANBioGRID21903422 details
MIB1_HUMANDAPK1_HUMANBioGRID, HPRD12351649 15048887 details
MIB1_HUMANCP131_HUMANBioGRID24121310 31462741 details
MIB1_HUMANBLM_HUMANBioGRID24239288 30044990 details
MIB1_HUMANE41LA_HUMANBioGRID27510968 details
MIB1_HUMANE41L5_HUMANBioGRID27510968 31462741 details
MIB1_HUMANWRN_HUMANBioGRID32652764 details
MIB1_HUMANDAB2_HUMANHPRD11812785 details
MIB1_HUMANPCM1_HUMANBioGRID, IntAct21956701 24121310 25795303 26638075 31462741 34079125 details
MIB1_HUMANRYK_HUMANBioGRID21875946 details
MIB1_HUMANDLL1_HUMANBioGRID21985982 27510968 details
MIB1_HUMANCMIP_HUMANBioGRID20018188 details
MIB1_HUMANSMN_HUMANBioGRID23615451 details
MIB1_HUMANMIB1_HUMANBioGRID24239288 details
MIB1_HUMANUSP9X_HUMANBioGRID24239288 31462741 details
MIB1_HUMANZC3H1_HUMANBioGRID24239288 details
MIB1_HUMANRAGP1_HUMANBioGRID24239288 details
MIB1_HUMANZBT10_HUMANBioGRID24239288 details
MIB1_HUMANGEMI4_HUMANBioGRID24239288 details
MIB1_HUMANMCM3_HUMANBioGRID24239288 details
MIB1_HUMANTOP3A_HUMANBioGRID24239288 details
MIB1_HUMANDDB1_HUMANBioGRID24239288 details
MIB1_HUMANTOP3B_HUMANBioGRID24239288 31462741 details
MIB1_HUMANRBBP4_HUMANBioGRID24239288 details
MIB1_HUMANMCM7_HUMANBioGRID24239288 details
MIB1_HUMANCDC27_HUMANBioGRID24239288 details
MIB1_HUMANPLK4_HUMANBioGRID25795303 details
MIB1_HUMANCYLD_HUMANBioGRID31067453 31462741 details
MIB1_HUMANST7_HUMANBioGRID29395067 31462741 details
MIB1_HUMANTNR6A_HUMANBioGRID29395067 31462741 details
MIB1_HUMANZO1_HUMANBioGRID31462741 details
MIB1_HUMANCRUM1_HUMANBioGRID31462741 details
MIB1_HUMANCRUM3_HUMANBioGRID31462741 details
MIB1_HUMANF120C_HUMANBioGRID29395067 details