Entity Details

Primary name SYCP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IZU3
EntryNameSYCP3_HUMAN
FullNameSynaptonemal complex protein 3
TaxID9606
Evidenceevidence at protein level
Length236
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesSYCP3

GO terms

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GOName
GO:0000775 chromosome, centromeric region
GO:0000795 synaptonemal complex
GO:0000800 lateral element
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0007141 male meiosis I
GO:0007286 spermatid development
GO:0035093 spermatogenesis, exchange of chromosomal proteins
GO:0051301 cell division
GO:0051321 meiotic cell cycle

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR006888 XLR/SYCP3/FAM9 domainDomainDomain

Diseases

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Disease IDSourceNameDescription
270960 OMIMSpermatogenic failure 4 (SPGF4)An infertility disorder characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes. The disease is caused by variants affecting the gene represented in this entry.
270960 OMIMSpermatogenic failure 4 (SPGF4)An infertility disorder characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes. Disease susceptibility is associated with variants affecting the gene represented in this entry.