Entity Details

Primary name LTBP4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N2S1
EntryNameLTBP4_HUMAN
FullNameLatent-transforming growth factor beta-binding protein 4
TaxID9606
Evidenceevidence at protein level
Length1624
SequenceStatuscomplete
DateCreated2007-11-13
DateModified2021-06-02

Ontological Relatives

GenesLTBP4

GO terms

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GOName
GO:0001527 microfibril
GO:0001558 regulation of cell growth
GO:0005024 transforming growth factor beta-activated receptor activity
GO:0005178 integrin binding
GO:0005509 calcium ion binding
GO:0005539 glycosaminoglycan binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006457 protein folding
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0007275 multicellular organism development
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
GO:0030162 regulation of proteolysis
GO:0030252 growth hormone secretion
GO:0031012 extracellular matrix
GO:0045595 regulation of cell differentiation
GO:0048251 elastic fiber assembly
GO:0050431 transforming growth factor beta binding
GO:0062023 collagen-containing extracellular matrix

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000152 EGF-type aspartate/asparagine hydroxylation sitePTMPTM
IPR000742 EGF-like domainDomainDomain
IPR001881 EGF-like calcium-binding domainDomainDomain
IPR009030 Growth factor receptor cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR013032 EGF-like, conserved siteSiteConserved site
IPR017878 TB domainDomainDomain
IPR018097 EGF-like calcium-binding, conserved siteSiteConserved site
IPR036773 TGF-beta binding (TB) domain superfamilyFamilyHomologous superfamily

Diseases

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