Entity Details

Primary name DP13B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NEU8
EntryNameDP13B_HUMAN
FullNameDCC-interacting protein 13-beta
TaxID9606
Evidenceevidence at protein level
Length664
SequenceStatuscomplete
DateCreated2005-03-15
DateModified2021-06-02

Ontological Relatives

GenesAPPL2

GO terms

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GOName
GO:0001726 ruffle
GO:0001786 phosphatidylserine binding
GO:0002024 diet induced thermogenesis
GO:0005634 nucleus
GO:0005768 endosome
GO:0005886 plasma membrane
GO:0006606 protein import into nucleus
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0009631 cold acclimation
GO:0010008 endosome membrane
GO:0010762 regulation of fibroblast migration
GO:0016020 membrane
GO:0023052 signaling
GO:0031410 cytoplasmic vesicle
GO:0031901 early endosome membrane
GO:0031982 vesicle
GO:0032009 early phagosome
GO:0032587 ruffle membrane
GO:0033211 adiponectin-activated signaling pathway
GO:0034143 regulation of toll-like receptor 4 signaling pathway
GO:0035091 phosphatidylinositol binding
GO:0035729 cellular response to hepatocyte growth factor stimulus
GO:0036186 early phagosome membrane
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0044354 macropinosome
GO:0044877 protein-containing complex binding
GO:0045088 regulation of innate immune response
GO:0046322 negative regulation of fatty acid oxidation
GO:0046325 negative regulation of glucose import
GO:0050768 negative regulation of neurogenesis
GO:0051289 protein homotetramerization
GO:0060100 positive regulation of phagocytosis, engulfment
GO:0070062 extracellular exosome
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1900016 negative regulation of cytokine production involved in inflammatory response
GO:1900077 negative regulation of cellular response to insulin stimulus
GO:1905303 positive regulation of macropinocytosis
GO:1905451 positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis
GO:2000045 regulation of G1/S transition of mitotic cell cycle
GO:2000178 negative regulation of neural precursor cell proliferation

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic vesicle
Early endosome membrane
Endosome membrane
Nucleus

Domains

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DomainNameCategoryType
IPR001849 Pleckstrin homology domainDomainDomain
IPR006020 PTB/PI domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR027267 AH/BAR domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
DP13B_HUMANDP13A_HUMANBioGRID, HPRD, IntAct, UniProt15016378 16189514 17030088 18034774 23414517 24879834 25416956 28514442 31515488 32296183 details
DP13B_HUMANRB22A_HUMANBioGRID, HPRD, IntAct16189514 25416956 31515488 32296183 details
DP13B_HUMANRBBP7_HUMANBioGRID, HPRD, IntAct15016378 details
DP13B_HUMANMTA2_HUMANBioGRID, HPRD, IntAct15016378 details
DP13B_HUMANSUV92_HUMANBioGRID, IntAct, MINT23455924 25416956 31515488 32296183 details
DP13B_HUMANLST8_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANKMT2C_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANMARE3_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANLIX1_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANLEG9B_HUMANIntAct25814554 details
DP13B_HUMANRAI2_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANLDH6B_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANPINK1_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANCRBN_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANRET7_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANTSC1_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANCRLF3_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANCQ082_HUMANIntAct25814554 details
DP13B_HUMANDOK3_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANATF3_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANCNMD_HUMANBioGRID, IntAct25814554 details
DP13B_HUMANRAB5C_HUMANBioGRID, IntAct25416956 31515488 32296183 34079125 details
DP13B_HUMANCRADD_HUMANBioGRID, IntAct25416956 31515488 details
DP13B_HUMANTINF2_HUMANbhf-ucl, BioGRID21044950 details
DP13B_HUMANPOTE1_HUMANbhf-ucl, BioGRID21044950 details
DP13B_HUMANKIFC3_HUMANBioGRID, IntAct32296183 details
DP13B_HUMANPRR35_HUMANBioGRID, IntAct32296183 details
DP13B_HUMANEPMIP_HUMANBioGRID, IntAct32296183 details
DP13B_HUMANRAB5A_HUMANBioGRID, HPRD, IntAct, UniProt15016378 18034774 29568061 34079125 details
DP13B_HUMANDP13B_HUMANUniProt18034774 details
DP13B_HUMANRUVB2_HUMANBioGRID19433865 details
DP13B_HUMANLEG9C_HUMANBioGRID25814554 details
DP13B_HUMANTBCD1_HUMANUniProt24879834 details
DP13B_HUMANFMR1_HUMANIntAct31413325 details
DP13B_HUMANFSHR_HUMANBioGRID17030088 details