Entity Details

Primary name FBH1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NFZ0
EntryNameFBH1_HUMAN
FullNameF-box DNA helicase 1
TaxID9606
Evidenceevidence at protein level
Length1043
SequenceStatuscomplete
DateCreated2004-03-15
DateModified2021-06-02

Ontological Relatives

GenesFBH1

GO terms

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GOName
GO:0000724 double-strand break repair via homologous recombination
GO:0000725 recombinational repair
GO:0000737 DNA catabolic process, endonucleolytic
GO:0000785 chromatin
GO:0001934 positive regulation of protein phosphorylation
GO:0003678 DNA helicase activity
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0006974 cellular response to DNA damage stimulus
GO:0008219 cell death
GO:0015616 DNA translocase activity
GO:0016567 protein ubiquitination
GO:0019005 SCF ubiquitin ligase complex
GO:0031297 replication fork processing
GO:0035562 negative regulation of chromatin binding
GO:0043138 3'-5' DNA helicase activity
GO:0048478 replication fork protection
GO:0072429 response to intra-S DNA damage checkpoint signaling
GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:2000042 negative regulation of double-strand break repair via homologous recombination

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR000212 DNA helicase, UvrD/REP typeFamilyFamily
IPR001810 F-box domainDomainDomain
IPR014017 UvrD-like DNA helicase, C-terminalDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036047 F-box-like domain superfamilyFamilyHomologous superfamily

Diseases

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