Entity Details

Primary name GSDMB_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TAX9
EntryNameGSDMB_HUMAN
FullNameGasdermin-B
TaxID9606
Evidenceevidence at protein level
Length411
SequenceStatuscomplete
DateCreated2008-04-08
DateModified2021-06-02

Ontological Relatives

GenesGSDMB

GO terms

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GOName
GO:0001786 phosphatidylserine binding
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0019835 cytolysis
GO:0022829 wide pore channel activity
GO:0042742 defense response to bacterium
GO:0070269 pyroptosis
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0140507 granzyme-mediated programmed cell death signaling pathway
GO:1902483 cytotoxic T cell pyroptotic process

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR007677 GasderminFamilyFamily
IPR040460 Gasdermin, pore forming domainDomainDomain
IPR041263 Gasdermin, PUB domainDomainDomain

Diseases

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