Entity Details

Primary name PPP6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO00743
EntryNamePPP6_HUMAN
FullNameSerine/threonine-protein phosphatase 6 catalytic subunit
TaxID9606
Evidenceevidence at protein level
Length305
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPPP6C

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0004722 protein serine/threonine phosphatase activity
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0007004 telomere maintenance via telomerase
GO:0045087 innate immune response
GO:0046872 metal ion binding
GO:0048208 COPII vesicle coating
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion

Domains

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DomainNameCategoryType
IPR004843 Calcineurin-like phosphoesterase domain, ApaH typeDomainDomain
IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphataseDomainDomain
IPR029052 Metallo-dependent phosphatase-likeFamilyHomologous superfamily

Diseases

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Interactions

26 interactions

InteractorPartnerSourcesPublicationsLink
PPP6_HUMANIGBP1_HUMANBioGRID, HPRD, IntAct, UniProt16085932 18186651 24255178 26496610 27684187 27880917 28330616 32296183 9647778 details
PPP6_HUMANTIPRL_HUMANBioGRID, IntAct, MINT16085932 17384681 24255178 27880917 details
PPP6_HUMANM3K7_HUMANBioGRID, MINT17079228 19955178 details
PPP6_HUMANPRKDC_HUMANBioGRID, IntAct20065038 24255178 27684187 28330616 details
PPP6_HUMANVAC14_HUMANBioGRID, IntAct32296183 details
PPP6_HUMANZNRF2_HUMANBioGRID27244671 details
PPP6_HUMANTRI14_HUMANBioGRID29053956 details
PPP6_HUMANIKBE_HUMANHPRD, IntAct14743216 details
PPP6_HUMANPP4C_HUMANIntAct17353931 details
PPP6_HUMANPP6R1_HUMANBioGRID, IntAct, MINT, UniProt16769727 18186651 20065038 21187329 24255178 27684187 27880917 28330616 details
PPP6_HUMANPP6R2_HUMANBioGRID, IntAct, MINT, UniProt16769727 18186651 20065038 21187329 24255178 27684187 27880917 28330616 28514442 details
PPP6_HUMANANR28_HUMANBioGRID, IntAct, MINT, UniProt18186651 21187329 24255178 27684187 27880917 28330616 details
PPP6_HUMANPP6R3_HUMANBioGRID, IntAct, MINT, UniProt18186651 20065038 21187329 22939629 24255178 26344197 27684187 27880917 28330616 details
PPP6_HUMANMOB1B_HUMANBioGRID, IntAct24255178 details
PPP6_HUMANARHG2_HUMANBioGRID, IntAct24255178 27684187 27880917 29089450 details
PPP6_HUMANTAB2_HUMANBioGRID19955178 details
PPP6_HUMANBRCA1_HUMANBioGRID22990118 26831064 details
PPP6_HUMANEFMT3_HUMANBioGRID23349634 details
PPP6_HUMANEGFR_HUMANBioGRID23956138 details
PPP6_HUMANABCE1_HUMANBioGRID25659154 details
PPP6_HUMANKC1D_HUMANBioGRID23864707 details
PPP6_HUMANDDX58_HUMANBioGRID29053956 details
PPP6_HUMANMAVS_HUMANBioGRID29053956 details
PPP6_HUMANWRIP1_HUMANBioGRID29053956 details
PPP6_HUMANUBP10_HUMANBioGRID29395067 details
PPP6_HUMANTGFR1_HUMANHPRD15761153 details