Entity Details

Primary name TGFA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WUH2
EntryNameTGFA1_HUMAN
FullNameTransforming growth factor-beta receptor-associated protein 1
TaxID9606
Evidenceevidence at protein level
Length860
SequenceStatuscomplete
DateCreated2008-07-22
DateModified2021-06-02

Ontological Relatives

GenesTGFBRAP1

GO terms

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GOName
GO:0005160 transforming growth factor beta receptor binding
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0006355 regulation of transcription, DNA-templated
GO:0006886 intracellular protein transport
GO:0006914 autophagy
GO:0007165 signal transduction
GO:0007179 transforming growth factor beta receptor signaling pathway
GO:0008333 endosome to lysosome transport
GO:0016020 membrane
GO:0033263 CORVET complex
GO:0034058 endosomal vesicle fusion
GO:0043231 intracellular membrane-bounded organelle
GO:0046332 SMAD binding

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome

Domains

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DomainNameCategoryType
IPR000547 Clathrin, heavy chain/VPS, 7-fold repeatRepeatRepeat
IPR001180 Citron homology (CNH) domainDomainDomain
IPR019452 Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1DomainDomain
IPR019453 Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2DomainDomain
IPR032914 Vam6/VPS39/TRAP1 familyFamilyFamily

Diseases

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