Entity Details

Primary name RXFP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WXD0
EntryNameRXFP2_HUMAN
FullNameRelaxin receptor 2
TaxID9606
Evidenceevidence at protein level
Length754
SequenceStatuscomplete
DateCreated2002-06-06
DateModified2021-06-02

Ontological Relatives

GenesRXFP2

GO terms

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GOName
GO:0001556 oocyte maturation
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0008285 negative regulation of cell population proliferation
GO:0008528 G protein-coupled peptide receptor activity
GO:0008584 male gonad development
GO:0009755 hormone-mediated signaling pathway
GO:0016500 protein-hormone receptor activity
GO:0017046 peptide hormone binding
GO:0043066 negative regulation of apoptotic process
GO:0043950 positive regulation of cAMP-mediated signaling

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001611 Leucine-rich repeatRepeatRepeat
IPR002172 Low-density lipoprotein (LDL) receptor class A repeatRepeatRepeat
IPR003591 Leucine-rich repeat, typical subtypeRepeatRepeat
IPR008112 Relaxin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain
IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved siteSiteConserved site
IPR032675 Leucine-rich repeat domain superfamilyFamilyHomologous superfamily
IPR036055 LDL receptor-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions