Entity Details

Primary name AP2B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ92481
EntryNameAP2B_HUMAN
FullNameTranscription factor AP-2-beta
TaxID9606
Evidenceevidence at protein level
Length460
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesTFAP2B

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001822 kidney development
GO:0003091 renal water homeostasis
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006006 glucose metabolic process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0010842 retina layer formation
GO:0010960 magnesium ion homeostasis
GO:0030510 regulation of BMP signaling pathway
GO:0035136 forelimb morphogenesis
GO:0035137 hindlimb morphogenesis
GO:0035810 positive regulation of urine volume
GO:0035909 aorta morphogenesis
GO:0042127 regulation of cell population proliferation
GO:0042493 response to drug
GO:0042593 glucose homeostasis
GO:0042803 protein homodimerization activity
GO:0043066 negative regulation of apoptotic process
GO:0043524 negative regulation of neuron apoptotic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0043588 skin development
GO:0045444 fat cell differentiation
GO:0045595 regulation of cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0048485 sympathetic nervous system development
GO:0048856 anatomical structure development
GO:0050796 regulation of insulin secretion
GO:0055062 phosphate ion homeostasis
GO:0055074 calcium ion homeostasis
GO:0055075 potassium ion homeostasis
GO:0055078 sodium ion homeostasis
GO:0072017 distal tubule development
GO:0072044 collecting duct development
GO:0072210 metanephric nephron development
GO:0097070 ductus arteriosus closure
GO:0097275 cellular ammonium homeostasis
GO:0097276 cellular creatinine homeostasis
GO:0097277 cellular urea homeostasis
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR004979 Transcription factor AP-2FamilyFamily
IPR008122 Transcription factor AP-2 betaFamilyFamily
IPR013854 Transcription factor AP-2, C-terminalDomainDomain

Diseases

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