Entity Details

Primary name UHRF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96PU4
EntryNameUHRF2_HUMAN
FullNameE3 ubiquitin-protein ligase UHRF2
TaxID9606
Evidenceevidence at protein level
Length802
SequenceStatuscomplete
DateCreated2005-06-07
DateModified2021-06-02

Ontological Relatives

GenesUHRF2

GO terms

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GOName
GO:0000792 heterochromatin
GO:0003677 DNA binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005721 pericentric heterochromatin
GO:0007049 cell cycle
GO:0008134 transcription factor binding
GO:0010216 maintenance of DNA methylation
GO:0016567 protein ubiquitination
GO:0030154 cell differentiation
GO:0042393 histone binding
GO:0046872 metal ion binding
GO:0051726 regulation of cell cycle
GO:0051865 protein autoubiquitination
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000626 Ubiquitin-like domainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003105 SRA-YDGDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR015947 PUA-like superfamilyFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR021991 UHRF1, tandem tudor domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036987 SRA-YDG superfamilyFamilyHomologous superfamily

Diseases

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Interactions

60 interactions

InteractorPartnerSourcesPublicationsLink
UHRF2_HUMANSMAD4_HUMANBioGRID, HPRD, MINT15231748 details
UHRF2_HUMANCDK2_HUMANBioGRID, HPRD, IntAct, UniProt15178429 21952639 details
UHRF2_HUMANUB2D2_HUMANBioGRID, IntAct19690564 details
UHRF2_HUMANUB2D3_HUMANBioGRID, IntAct19690564 27114453 30392931 details
UHRF2_HUMANUB2D4_HUMANBioGRID, IntAct19690564 details
UHRF2_HUMANUBE2W_HUMANBioGRID, IntAct19690564 details
UHRF2_HUMANTRI27_HUMANBioGRID, IntAct22493164 details
UHRF2_HUMANHOIL1_HUMANBioGRID, IntAct22493164 details
UHRF2_HUMANTRIM8_HUMANBioGRID, IntAct22493164 details
UHRF2_HUMANLCK_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANJAK3_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANB2CL1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANCDK6_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANPTPRC_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANTYY1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANCD27_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANMCL1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANSKP1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANHDAC1_HUMANBioGRID, UniProt15361834 21952639 27114453 27743347 details
UHRF2_HUMANLYN_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANCTNB1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANBAX_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANFYN_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANRB_HUMANBioGRID, UniProt21952639 27114453 details
UHRF2_HUMANPCNA_HUMANBioGRID, UniProt21952639 27114453 28951215 details
UHRF2_HUMANPTEN_HUMANUniProt21952639 details
UHRF2_HUMANBCAR1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANCDK4_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANCDK1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANP53_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANRAD51_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANCCNE1_HUMANBioGRID, UniProt15178429 21952639 details
UHRF2_HUMANCCNA2_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANCCND1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANCCNB1_HUMANBioGRID, UniProt21952639 details
UHRF2_HUMANATX1_HUMANBioGRID, IntAct23275563 details
UHRF2_HUMANZN410_HUMANBioGRID, IntAct32296183 details
UHRF2_HUMANDESI1_HUMANBioGRID, IntAct32296183 details
UHRF2_HUMANHMGB1_HUMANUniProt31694235 32867128 details
UHRF2_HUMANHMGB2_HUMANUniProt31694235 details
UHRF2_HUMANUBE2K_HUMANBioGRID19549727 details
UHRF2_HUMANPCNP_HUMANBioGRID, HPRD12176013 14741369 27114453 details
UHRF2_HUMANH31_HUMANBioGRID22064703 28004105 29506131 details
UHRF2_HUMANUHRF1_HUMANBioGRID22411829 30335751 details
UHRF2_HUMANUB2D1_HUMANBioGRID14741369 21952639 29506131 details
UHRF2_HUMANUBP7_HUMANBioGRID23105109 27114453 27129234 details
UHRF2_HUMANUHRF2_HUMANBioGRID, HPRD14741369 29506131 details
UHRF2_HUMANZN618_HUMANBioGRID27129234 details
UHRF2_HUMANFACD2_HUMANBioGRID27114453 30335751 details
UHRF2_HUMANRUNX1_HUMANBioGRID28536267 details
UHRF2_HUMANDNMT1_HUMANBioGRID22064703 27114453 29691401 details
UHRF2_HUMANDNM3A_HUMANBioGRID22064703 details
UHRF2_HUMANDNM3B_HUMANBioGRID22064703 details
UHRF2_HUMANEHMT2_HUMANBioGRID22064703 27114453 details
UHRF2_HUMANZN131_HUMANBioGRID23404503 details
UHRF2_HUMANUBC9_HUMANBioGRID23404503 details
UHRF2_HUMAN3MG_HUMANBioGRID23537643 details
UHRF2_HUMANE2F1_HUMANBioGRID23833190 details
UHRF2_HUMANKAT5_HUMANBioGRID27743347 details
UHRF2_HUMANCDN1A_HUMANBioGRID29923055 details