Entity Details

Primary name RHG07_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96QB1
EntryNameRHG07_HUMAN
FullNameRho GTPase-activating protein 7
TaxID9606
Evidenceevidence at protein level
Length1528
SequenceStatuscomplete
DateCreated2002-11-08
DateModified2021-06-02

Ontological Relatives

GenesDLC1

GO terms

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GOName
GO:0001843 neural tube closure
GO:0003007 heart morphogenesis
GO:0005096 GTPase activator activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005901 caveola
GO:0005925 focal adhesion
GO:0006915 apoptotic process
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 signal transduction
GO:0008285 negative regulation of cell population proliferation
GO:0008289 lipid binding
GO:0008360 regulation of cell shape
GO:0021575 hindbrain morphogenesis
GO:0030036 actin cytoskeleton organization
GO:0030336 negative regulation of cell migration
GO:0030864 cortical actin cytoskeleton
GO:0030900 forebrain development
GO:0032587 ruffle membrane
GO:0032956 regulation of actin cytoskeleton organization
GO:0035023 regulation of Rho protein signal transduction
GO:0035024 negative regulation of Rho protein signal transduction
GO:0035307 positive regulation of protein dephosphorylation
GO:0042169 SH2 domain binding
GO:0045121 membrane raft
GO:0048041 focal adhesion assembly
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051497 negative regulation of stress fiber assembly
GO:0051895 negative regulation of focal adhesion assembly
GO:1900119 positive regulation of execution phase of apoptosis

Subcellular Location

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Subcellular Location
Cell junction
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000198 Rho GTPase-activating protein domainDomainDomain
IPR001660 Sterile alpha motif domainDomainDomain
IPR002913 START domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR013761 Sterile alpha motif/pointed domain superfamilyFamilyHomologous superfamily
IPR023393 START-like domain superfamilyFamilyHomologous superfamily
IPR028854 Rho GTPase-activating protein 7FamilyFamily

Diseases

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Interactions

51 interactions

InteractorPartnerSourcesPublicationsLink
RHG07_HUMANRASA1_HUMANBioGRID, MINT19151751 24412244 details
RHG07_HUMANBACH_HUMANBioGRID, MINT24412244 details
RHG07_HUMANKPYM_HUMANBioGRID, MINT24412244 details
RHG07_HUMANPFKAM_HUMANBioGRID, MINT24412244 details
RHG07_HUMANTM129_HUMANBioGRID, MINT24412244 details
RHG07_HUMANRAGP1_HUMANBioGRID, MINT24412244 details
RHG07_HUMANBAAT_HUMANBioGRID, MINT24412244 details
RHG07_HUMANTRMO_HUMANBioGRID, MINT24412244 details
RHG07_HUMANAMPO_HUMANBioGRID, MINT24412244 details
RHG07_HUMANCC14B_HUMANBioGRID, MINT24412244 details
RHG07_HUMANCOR2A_HUMANBioGRID, MINT24412244 details
RHG07_HUMANCATL2_HUMANBioGRID, MINT24412244 details
RHG07_HUMANFANCC_HUMANBioGRID, MINT24412244 details
RHG07_HUMANHEMGN_HUMANBioGRID, MINT24412244 details
RHG07_HUMANF16P2_HUMANBioGRID, MINT24412244 details
RHG07_HUMANDHB3_HUMANBioGRID, MINT24412244 details
RHG07_HUMANCC180_HUMANBioGRID, MINT24412244 details
RHG07_HUMANMAPK3_HUMANMINT24412244 details
RHG07_HUMANCANB2_HUMANBioGRID, MINT24412244 details
RHG07_HUMANSFRP4_HUMANBioGRID, MINT24412244 details
RHG07_HUMANSMAD1_HUMANBioGRID, MINT24412244 details
RHG07_HUMANSTX17_HUMANBioGRID, MINT24412244 details
RHG07_HUMANTDRD7_HUMANBioGRID, MINT24412244 details
RHG07_HUMANTGFB1_HUMANBioGRID, MINT24412244 details
RHG07_HUMANTEFF1_HUMANBioGRID, MINT24412244 details
RHG07_HUMANTMOD1_HUMANBioGRID, MINT24412244 details
RHG07_HUMANXPA_HUMANBioGRID, MINT24412244 details
RHG07_HUMANZN189_HUMANBioGRID, MINT24412244 details
RHG07_HUMANZN510_HUMANBioGRID, MINT24412244 details
RHG07_HUMANTENS1_HUMANDIP17517630 details
RHG07_HUMANKIBRA_HUMANBioGRID16684779 24682284 details
RHG07_HUMANTNS2_HUMANBioGRID16951145 details
RHG07_HUMANAKT1_HUMANBioGRID, HPRD16338927 details
RHG07_HUMANKS6A1_HUMANBioGRID16338927 details
RHG07_HUMANPTEN_HUMANBioGRID19482022 details
RHG07_HUMANMK03_HUMANBioGRID24412244 details
RHG07_HUMANUBP4_HUMANBioGRID24412244 details
RHG07_HUMANRHOA_HUMANBioGRID32203420 details
RHG07_HUMANTENS3_HUMANIntAct19732724 details
RHG07_HUMANDISC1_HUMANIntAct31413325 details
RHG07_HUMANS10AA_HUMANBioGRID21372205 details
RHG07_HUMANCAV1_HUMANBioGRID16951145 22693251 details
RHG07_HUMANCUL1_HUMANBioGRID24082123 details
RHG07_HUMANCUL2_HUMANBioGRID24082123 details
RHG07_HUMANCUL3_HUMANBioGRID24082123 details
RHG07_HUMANCUL4A_HUMANBioGRID24082123 details
RHG07_HUMANDDB1_HUMANBioGRID24082123 details
RHG07_HUMANFBXW5_HUMANBioGRID24082123 details
RHG07_HUMANWWC2_HUMANBioGRID24682284 details
RHG07_HUMANWWC3_HUMANBioGRID24682284 details
RHG07_HUMANSTA13_HUMANBioGRID32203420 details