Entity Details

Primary name SEBP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96T21
EntryNameSEBP2_HUMAN
FullNameSelenocysteine insertion sequence-binding protein 2
TaxID9606
Evidenceevidence at protein level
Length854
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesSECISBP2

GO terms

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GOName
GO:0001514 selenocysteine incorporation
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0021756 striatum development
GO:0035368 selenocysteine insertion sequence binding
GO:0043021 ribonucleoprotein complex binding
GO:0048666 neuron development
GO:1990904 ribonucleoprotein complex
GO:2000623 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Subcellular Location

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Subcellular Location
Mitochondrion
Nucleus

Domains

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DomainNameCategoryType
IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45DomainDomain
IPR029064 50S ribosomal protein L30e-likeFamilyHomologous superfamily
IPR040051 Selenocysteine insertion sequence-binding protein 2FamilyFamily

Diseases

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Disease IDSourceNameDescription
609698 OMIMThyroid hormone metabolism, abnormal (THMA)A disorder associated with a reduction in type II iodothyronine deiodinase activity. The disease is caused by variants affecting the gene represented in this entry.

Interactions

40 interactions

InteractorPartnerSourcesPublicationsLink
SEBP2_HUMANSMAD9_HUMANBioGRID, HPRD, MINT15231748 details
SEBP2_HUMANAT7L3_HUMANBioGRID, HPRD, IntAct16713569 details
SEBP2_HUMANGOGA2_HUMANBioGRID, IntAct25416956 details
SEBP2_HUMANF168A_HUMANBioGRID, IntAct32296183 details
SEBP2_HUMANHD_HUMANIntAct32814053 details
SEBP2_HUMANA4_HUMANBioGRID21244100 21832049 details
SEBP2_HUMANFXR1_HUMANBioGRID29395067 details
SEBP2_HUMANLZTS2_HUMANBioGRID29395067 details
SEBP2_HUMANMEX3B_HUMANBioGRID29395067 details
SEBP2_HUMANMKRN2_HUMANBioGRID29395067 details
SEBP2_HUMANMOV10_HUMANBioGRID29395067 details
SEBP2_HUMANOTUD4_HUMANBioGRID29395067 details
SEBP2_HUMANPABP1_HUMANBioGRID29395067 details
SEBP2_HUMANPRC2A_HUMANBioGRID29395067 details
SEBP2_HUMANPUM1_HUMANBioGRID29395067 details
SEBP2_HUMANR3HD2_HUMANBioGRID29395067 details
SEBP2_HUMANRBM47_HUMANBioGRID29395067 details
SEBP2_HUMANRBMS1_HUMANBioGRID29395067 details
SEBP2_HUMANSTAU1_HUMANBioGRID29395067 details
SEBP2_HUMANTDRD3_HUMANBioGRID29395067 details
SEBP2_HUMANUBP2L_HUMANBioGRID29395067 details
SEBP2_HUMANYTHD1_HUMANBioGRID29395067 details
SEBP2_HUMANYTHD2_HUMANBioGRID29395067 details
SEBP2_HUMANYTHD3_HUMANBioGRID29395067 details
SEBP2_HUMANZCCHV_HUMANBioGRID29395067 details
SEBP2_HUMANTTP_HUMANBioGRID29395067 details
SEBP2_HUMANANR17_HUMANBioGRID29395067 details
SEBP2_HUMANCAPR1_HUMANBioGRID29395067 details
SEBP2_HUMANCSDE1_HUMANBioGRID29395067 details
SEBP2_HUMANDDX3X_HUMANBioGRID29395067 details
SEBP2_HUMANFMR1_HUMANBioGRID29395067 details
SEBP2_HUMANPATL1_HUMANBioGRID29395067 details
SEBP2_HUMANSMAG2_HUMANBioGRID29395067 details
SEBP2_HUMANZ3H7A_HUMANBioGRID29395067 details
SEBP2_HUMANSMG7_HUMANBioGRID29395067 details
SEBP2_HUMANHNRPQ_HUMANBioGRID29395067 details
SEBP2_HUMANPAIP2_HUMANBioGRID29395067 details
SEBP2_HUMANRN214_HUMANBioGRID29395067 details
SEBP2_HUMANTOP3B_HUMANBioGRID29395067 details
SEBP2_HUMANXRN1_HUMANBioGRID29395067 details