Entity Details

Primary name PLXB2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15031
EntryNamePLXB2_HUMAN
FullNamePlexin-B2
TaxID9606
Evidenceevidence at protein level
Length1838
SequenceStatuscomplete
DateCreated2004-08-31
DateModified2021-06-02

Ontological Relatives

GenesPLXNB2

GO terms

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GOName
GO:0001843 neural tube closure
GO:0001932 regulation of protein phosphorylation
GO:0002116 semaphorin receptor complex
GO:0005887 integral component of plasma membrane
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007162 negative regulation of cell adhesion
GO:0007405 neuroblast proliferation
GO:0007420 brain development
GO:0008360 regulation of cell shape
GO:0009986 cell surface
GO:0010976 positive regulation of neuron projection development
GO:0017154 semaphorin receptor activity
GO:0030334 regulation of cell migration
GO:0043087 regulation of GTPase activity
GO:0045727 positive regulation of translation
GO:0050772 positive regulation of axonogenesis
GO:0070062 extracellular exosome
GO:0071526 semaphorin-plexin signaling pathway
GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance
GO:1904861 excitatory synapse assembly
GO:2001222 regulation of neuron migration

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001627 Sema domainDomainDomain
IPR002165 Plexin repeatRepeatRepeat
IPR002909 IPT domainDomainDomain
IPR008936 Rho GTPase activation proteinFamilyHomologous superfamily
IPR013548 Plexin, cytoplasmic RasGAP domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR031148 Plexin familyFamilyFamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily
IPR041019 Plexin, TIG domain 1DomainDomain

Diseases

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