Entity Details

Primary name TREX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BQ50
EntryNameTREX2_HUMAN
FullNameThree prime repair exonuclease 2
TaxID9606
Evidenceevidence at protein level
Length236
SequenceStatuscomplete
DateCreated2004-05-24
DateModified2021-06-02

Ontological Relatives

GenesTREX2

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0000738 DNA catabolic process, exonucleolytic
GO:0003676 nucleic acid binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0008296 3'-5'-exodeoxyribonuclease activity
GO:0008853 exodeoxyribonuclease III activity
GO:0042803 protein homodimerization activity

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR012337 Ribonuclease H-like superfamilyFamilyHomologous superfamily
IPR013520 Exonuclease, RNase T/DNA polymerase IIIDomainDomain
IPR034926 Three prime repair exonuclease 2FamilyFamily
IPR036397 Ribonuclease H superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
TREX2_HUMANMESD_HUMANBioGRID, IntAct32296183 details
TREX2_HUMANATF4_HUMANBioGRID16189514 details
TREX2_HUMANTREX2_HUMANBioGRID11279105 details