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Entity Details
Primary name
LST8_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
Q9BVC4
EntryName
LST8_HUMAN
FullName
Target of rapamycin complex subunit LST8
TaxID
9606
Evidence
evidence at protein level
Length
326
SequenceStatus
complete
DateCreated
2008-04-08
DateModified
2021-06-02
Ontological Relatives
Genes
MLST8
GO terms
Show/Hide Table
GO
Name
GO:0005654
nucleoplasm
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0016241
regulation of macroautophagy
GO:0031929
TOR signaling
GO:0031931
TORC1 complex
GO:0031932
TORC2 complex
GO:0032008
positive regulation of TOR signaling
GO:0032148
activation of protein kinase B activity
GO:0032956
regulation of actin cytoskeleton organization
GO:0034198
cellular response to amino acid starvation
GO:0038202
TORC1 signaling
GO:0043539
protein serine/threonine kinase activator activity
GO:1900034
regulation of cellular response to heat
GO:1901796
regulation of signal transduction by p53 class mediator
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR001680
WD40 repeat
Repeat
Repeat
IPR011047
Quinoprotein alcohol dehydrogenase-like superfamily
Family
Homologous superfamily
IPR015943
WD40/YVTN repeat-like-containing domain superfamily
Family
Homologous superfamily
IPR019775
WD40 repeat, conserved site
Site
Conserved site
IPR020472
G-protein beta WD-40 repeat
Repeat
Repeat
IPR037588
Target of rapamycin complex subunit LST8
Family
Family
Diseases
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Drugs
Show/Hide Table
Interactions
23 interactions
Interactor
Partner
Sources
Publications
Link
LST8_HUMAN
RICTR_HUMAN
BioGRID, IntAct
17461779
17565979
18030348
18505677
21376236
22084251
28489822
28514442
31665642
details
LST8_HUMAN
MTOR_HUMAN
BioGRID, DIP, HPRD, IntAct
12408816
12718876
12719976
15066126
15459249
16183647
16798736
17277771
17461779
18030348
18504440
18505677
19446321
20427287
20562859
21321085
22084251
22258093
23636326
26186194
26348909
26678875
27173435
28489822
28514442
32433973
unassigned1312
details
LST8_HUMAN
A2MG_HUMAN
BioGRID, IntAct
21163940
details
LST8_HUMAN
ATX1_HUMAN
BioGRID, IntAct
23275563
details
LST8_HUMAN
ANM1_HUMAN
BioGRID, MINT
23455924
details
LST8_HUMAN
DP13B_HUMAN
BioGRID, IntAct
25814554
details
LST8_HUMAN
4EBP1_HUMAN
BioGRID
18955708
details
LST8_HUMAN
SIN1_HUMAN
BioGRID, IntAct
17461779
28489822
details
LST8_HUMAN
DPTOR_HUMAN
BioGRID, IntAct
19446321
22017875
details
LST8_HUMAN
RPTOR_HUMAN
BioGRID, DIP, HPRD, IntAct
12408816
12718876
16798736
17565979
18030348
20169205
20562859
21321085
24403073
25940091
26678875
28489822
details
LST8_HUMAN
NUDC_HUMAN
IntAct
25036637
details
LST8_HUMAN
XPO4_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
LST8_HUMAN
XPO6_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
LST8_HUMAN
THADA_HUMAN
BioGRID, IntAct
27173435
unassigned1312
details
LST8_HUMAN
SQSTM_HUMAN
BioGRID
21981924
details
LST8_HUMAN
ULK1_HUMAN
BioGRID
21460630
details
LST8_HUMAN
STAT1_HUMAN
BioGRID
19553685
details
LST8_HUMAN
FKBP8_HUMAN
BioGRID
17991864
details
LST8_HUMAN
ZNRF2_HUMAN
BioGRID
27244671
details
LST8_HUMAN
OTU7B_HUMAN
BioGRID
28489822
details
LST8_HUMAN
LARP1_HUMAN
BioGRID
25940091
details
LST8_HUMAN
MUC18_HUMAN
BioGRID
31665642
details
LST8_HUMAN
LNP_HUMAN
BioGRID
32433973
details
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