Entity Details

Primary name THIC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BWD1
EntryNameTHIC_HUMAN
FullNameAcetyl-CoA acetyltransferase, cytosolic
TaxID9606
Evidenceevidence at protein level
Length397
SequenceStatuscomplete
DateCreated2004-09-13
DateModified2021-06-02

Ontological Relatives

GenesACAT2

GO terms

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GOName
GO:0003985 acetyl-CoA C-acetyltransferase activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006629 lipid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0006695 cholesterol biosynthetic process
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002155 ThiolaseFamilyFamily
IPR016039 Thiolase-likeFamilyHomologous superfamily
IPR020610 Thiolase, active siteSiteActive site
IPR020613 Thiolase, conserved siteSiteConserved site
IPR020616 Thiolase, N-terminalDomainDomain
IPR020617 Thiolase, C-terminalDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01915 S-HydroxycysteineDrugbanksmall molecule
DB01992 Coenzyme ADrugbanksmall molecule