Entity Details

Primary name SPTN4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H254
EntryNameSPTN4_HUMAN
FullNameSpectrin beta chain, non-erythrocytic 4
TaxID9606
Evidenceevidence at protein level
Length2564
SequenceStatuscomplete
DateCreated2001-11-16
DateModified2021-06-02

Ontological Relatives

GenesSPTBN4

GO terms

Show/Hide Table
GOName
GO:0000165 MAPK cascade
GO:0002028 regulation of sodium ion transport
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005543 phospholipid binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005884 actin filament
GO:0005886 plasma membrane
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0007605 sensory perception of sound
GO:0007628 adult walking behavior
GO:0008091 spectrin
GO:0009566 fertilization
GO:0010459 negative regulation of heart rate
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016192 vesicle-mediated transport
GO:0016363 nuclear matrix
GO:0016605 PML body
GO:0019226 transmission of nerve impulse
GO:0019902 phosphatase binding
GO:0021952 central nervous system projection neuron axonogenesis
GO:0030506 ankyrin binding
GO:0030507 spectrin binding
GO:0033135 regulation of peptidyl-serine phosphorylation
GO:0033268 node of Ranvier
GO:0033270 paranode region of axon
GO:0040018 positive regulation of multicellular organism growth
GO:0043025 neuronal cell body
GO:0043194 axon initial segment
GO:0043203 axon hillock
GO:0045162 clustering of voltage-gated sodium channels
GO:0051693 actin filament capping
GO:0061337 cardiac conduction
GO:0070062 extracellular exosome
GO:0070852 cell body fiber
GO:0072659 protein localization to plasma membrane
GO:0106006 cytoskeletal protein-membrane anchor activity

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR001589 Actinin-type actin-binding domain, conserved siteSiteConserved site
IPR001605 Pleckstrin homology domain, spectrin-typeDomainDomain
IPR001715 Calponin homology domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR016343 Spectrin, beta subunitFamilyFamily
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR036872 CH domain superfamilyFamilyHomologous superfamily
IPR041681 Pleckstrin homology domain 9DomainDomain

Diseases

Show/Hide Table