Entity Details

Primary name PARL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H300
EntryNamePARL_HUMAN
FullNamePresenilins-associated rhomboid-like protein, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length379
SequenceStatuscomplete
DateCreated2005-04-12
DateModified2021-06-02

Ontological Relatives

GenesPARL

GO terms

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GOName
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0006508 proteolysis
GO:0006851 mitochondrial calcium ion transmembrane transport
GO:0010821 regulation of mitochondrion organization
GO:0016021 integral component of membrane
GO:0030162 regulation of proteolysis
GO:0033619 membrane protein proteolysis
GO:1903214 regulation of protein targeting to mitochondrion
GO:2000377 regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane
Nucleus

Domains

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DomainNameCategoryType
IPR022764 Peptidase S54, rhomboid domainDomainDomain
IPR035952 Rhomboid-like superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions